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Massachusetts General Hospital

Total Trials
47
Recruiting
47
Phases
Phase 1, Phase 2, EARLY_Phase 1, Phase 4

Massachusetts General Hospital is a clinical research sponsor with 47 registered studies on ClinicalTrials.gov, of which 47 are actively recruiting participants. Research covers conditions including Celiac Disease, Depression Disorders, Depression - Major Depressive Disorder, Depression Disorder.

The trial portfolio spans Phase 1, Phase 2, EARLY_Phase 1 studies, reflecting a pipeline that may include early-stage safety evaluations, mid-stage efficacy assessments, and large-scale confirmatory trials. All studies listed here are sourced directly from ClinicalTrials.gov and updated daily.

Frequently Asked Questions — Massachusetts General Hospital

How many clinical trials has Massachusetts General Hospital sponsored?
ClinicalMetric currently tracks 47 clinical trials sponsored by Massachusetts General Hospital, of which 47 are actively recruiting participants. These trials cover conditions including Celiac Disease, Depression Disorders, Depression - Major Depressive Disorder. Trial counts are updated daily from ClinicalTrials.gov and reflect currently registered studies.
What therapeutic areas does Massachusetts General Hospital research focus on?
Massachusetts General Hospital clinical trials span Celiac Disease, Depression Disorders, Depression - Major Depressive Disorder, Depression Disorder, Depression Chronic, and additional conditions. The research pipeline includes Phase 1, Phase 2, EARLY_Phase 1 trials, reflecting work from early-stage safety evaluation through large-scale efficacy studies.
How do I participate in a Massachusetts General Hospital clinical trial?
To participate in a Massachusetts General Hospital trial, review the active studies listed on this page, check each trial's specific eligibility criteria on ClinicalTrials.gov, and contact the trial site directly—not the sponsor's headquarters. Trial sites are academic medical centers, hospitals, or specialized research clinics. Your physician can facilitate a referral. ClinicalMetric lists all Massachusetts General Hospital trials with current recruitment status updated daily.

Clinical Trials by Massachusetts General Hospital

NCT02061306
Recruiting

Celiac Disease Genomic Environmental Microbiome and Metabolomic Study

Celiac Disease
NCT07082998
Recruiting

Comparing the Efficacy of Heated Yoga and Sauna as a Treatment for Depression

Depression Disorders
NCT05222594
Recruiting

Computational Neuroscience of Language Processing in the Human Brain

Language
NCT06246942
Recruiting

Physiology of Human Brain Connectivity

Healthy
NCT06172907
Recruiting

A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers

Cancer
NCT06566430
Recruiting

PrEP My Way: A Hybrid Type 1 Clinical Effectiveness-implementation Trial to Promote PrEP Persistence Among Young Kenyan Women

HIV/AIDS
NCT05881239
Recruiting

Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD

Subjective Cognitive Concerns
NCT05966038
Recruiting

ALS/MND Natural History Study Data Repository

ALS
NCT04699747 Phase 1
Recruiting

Investigating the Utility of Demyelination Tracer [18F]3F4AP in Controls and Multiple Sclerosis Subjects

Multiple Sclerosis
NCT06576076
Recruiting

Cannabis, Linked Emotions, and Adolescent Risk Study

Cannabis Use
NCT05839535 Phase 2
Recruiting

Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA

Knee Osteoarthritis
NCT06067347
Recruiting

A Global Study of the PETAL Consortium

T-Cell and NK-Cell Neoplasm
NCT06289621
Recruiting

Brief Transdiagnostic Treatment for Anxiety Disorders and Post-traumatic Stress Disorder (PTSD) in South Africa

Anxiety Disorders
NCT06943534 Phase 2
Recruiting

Omalizumab Weight-Based Dosing Efficacy Trial

Allergies
NCT05776641
Recruiting

Gamma Light and Sound Stimulation to Prevent Dementia in Cognitively Normal People at Risk for Alzheimer's Disease

Alzheimer Disease
NCT06950294 EARLY_Phase 1
Recruiting

iNO300 Therapy in Critically Ill Patients With Pneumonia

Critical Illness
NCT03830801
Recruiting

Pilot Study for OCT Guided In Vivo Laser Capture Microdissection for Assessing the Prognosis of Barrett's Esophagus

Barrett Esophagus
NCT06386588
Recruiting

The Effects of Auditory Stimulation During Sleep on Brain Networks in Schizophrenia

Schizophrenia
NCT05793541
Recruiting

Just-in-time Interventions for Reducing Short-term Suicide Risk

Suicide
NCT06432790
Recruiting

Comparative-effectiveness of a Healthy Lifestyle and Asthma Management Program, In-person vs. ONline

Overweight, Childhood
NCT07613840
Recruiting

Personalizing Thromboprophylaxis for Patients With Peripheral Artery Disease

Peripheral Arterial Disease (PAD)
NCT07568509 EARLY_Phase 1
Recruiting

Identifying Oxytocin Deficiency in Pediatric Patients With Pituitary Disease

Arginine Vasopressin Deficiency
NCT07211217
Recruiting

Time Restricted Eating (TRE) in Bipolar Disorder

Bipolar Disorder (BD)
NCT04875702 Phase 4
Recruiting

Treat-to-Target Serum Urate Versus Treat-to-Avoid Symptoms in Gout

Gout
NCT04296604
Recruiting

Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

Traumatic Brain Injury
NCT07563868
Recruiting

Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression

Treatment Resistant Depression (TRD)
NCT06226155
Recruiting

Adaptation of an Intervention Addressing Barriers to PrEP Use Among Pregnant Women in Zimbabwe

HIV Infections
NCT03694691
Recruiting

Developing Viability Index for Machine Perfused Livers

Liver Cirrhoses
NCT06811272 Phase 2
Recruiting

Outpatient Epcoritamab as 2L in NTE R/R DLBCL

Relapsed Large B-cell Lymphoma
NCT06998485
Recruiting

Substrates for Post-Stroke Arm Rehabilitation

Stroke Rehabilitation
NCT06429293
Recruiting

Impact of Cognitive Behavioral Therapy on PTSD-CVD Link

Posttraumatic Stress Disorder
NCT07091032
Recruiting

Building Connections

Cancer Colorectal
NCT07032714 Phase 1
Recruiting

Mezigdomide and Talquetamab in Relapsed and Refractory Multiple Myeloma

Relapsed Refractory Multiple Myeloma (RRMM)
NCT06915662 Phase 2
Recruiting

Pain Outcomes After Digital Amputation Using Tulavi Allay™ Nerve Cap

Neuroma
NCT05304286
Recruiting

Psychophysical and Neural Mechanisms Contributing to Chronic Post-Surgical Pain in Adolescents and Adults

Chronic Post-surgical Pain
NCT05674357
Recruiting

Training in Evidence-based Treatments in Psycho-Oncology

Distress, Emotional
NCT05129605
Recruiting

Prostate Cancer Genetic Risk Evaluation and Screening Study

Prostatic Neoplasm
NCT07118722
Recruiting

Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus Study

Chronic Pain
NCT06967545
Recruiting

A One-Arm Open Trial of a Smartphone Delivered Treatment for Suicidal Thoughts and Behavior

Suicide Attempt
NCT05332639
Recruiting

Personalized Risk Estimation for Crohn's Disease (PRE-Crohn's): Implementation and Feasibility

Inflammatory Bowel Diseases
NCT06538311 EARLY_Phase 1
Recruiting

Transcranial Magnetic Stimulation Treatment for Alzheimer's Disease

Alzheimer Disease
NCT06832865 Phase 2
Recruiting

ELISA in Relapsed/Refractory MM

Relapsed Refractory Multiple Myeloma (RRMM)
NCT05237258
Recruiting

Specialty Compared to Oncology Delivered Palliative Care for Patients With Acute Myeloid Leukemia

Relapsed Adult AML
NCT06136546 Phase 2
Recruiting

Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab

Depressive Disorder, Major
NCT06440135 Phase 1
Recruiting

Ziftomenib Maintenance Post Allo-HCT

Acute Myeloid Leukemia
NCT03029325
Recruiting

Molecular and Genetic Analysis of Lung Cancer

Lung Cancer
NCT06262113
Recruiting

A Decentralized Clinical Trial to Promote Evidence-Based Care for Underserved Patients With Neurofibromatosis 1

Neurofibromatosis 1
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology