SPONSOR

Massachusetts General Hospital

Total Trials

Recruiting

Phases

Phase 2, Phase 4, Phase 1, Phase 2, EARLY_Phase 1, Phase 3

Conditions studied: HIV-1-infection Frailty Impaired Physical Function Abdominal Obesity Aging Treatment Resistant Depression (TRD)Fuchs Endothelial Corneal Dysfunction Open Angle Glaucoma (OAG)Dry Eye Disease (DED)Keratoconus

Massachusetts General Hospital is a clinical research sponsor with 48 registered studies on ClinicalTrials.gov, of which 48 are actively recruiting participants. Research covers conditions including HIV-1-infection, Frailty, Impaired Physical Function, Abdominal Obesity.

The trial portfolio spans Phase 2, Phase 4, Phase 1, Phase 2 studies, reflecting a pipeline that may include early-stage safety evaluations, mid-stage efficacy assessments, and large-scale confirmatory trials. All studies listed here are sourced directly from ClinicalTrials.gov and updated daily.

Frequently Asked Questions — Massachusetts General Hospital

How many clinical trials has Massachusetts General Hospital sponsored?

ClinicalMetric currently tracks 48 clinical trials sponsored by Massachusetts General Hospital, of which 48 are actively recruiting participants. These trials cover conditions including HIV-1-infection, Frailty, Impaired Physical Function. Trial counts are updated daily from ClinicalTrials.gov and reflect currently registered studies.

What therapeutic areas does Massachusetts General Hospital research focus on?

Massachusetts General Hospital clinical trials span HIV-1-infection, Frailty, Impaired Physical Function, Abdominal Obesity, Aging, and additional conditions. The research pipeline includes Phase 2, Phase 4, Phase 1, Phase 2 trials, reflecting work from early-stage safety evaluation through large-scale efficacy studies.

How do I participate in a Massachusetts General Hospital clinical trial?

To participate in a Massachusetts General Hospital trial, review the active studies listed on this page, check each trial's specific eligibility criteria on ClinicalTrials.gov, and contact the trial site directly—not the sponsor's headquarters. Trial sites are academic medical centers, hospitals, or specialized research clinics. Your physician can facilitate a referral. ClinicalMetric lists all Massachusetts General Hospital trials with current recruitment status updated daily.

Massachusetts General Hospital

Frequently Asked Questions — Massachusetts General Hospital

Clinical Trials by Massachusetts General Hospital

Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression

A Study to Assess Brillouin Hydration Mapping for the Evaluation of Ocular Tissues and Diseases

Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via Infliximab

OBSERVE: Biomarkers in Individuals at Risk for Prion Disease

A Randomized Clinical Trial to Evaluate Solutions for the Management of Virologic Failure on TLD in Sub-Saharan Africa

BMT-CARE: Psychosocial Intervention for Transplant Caregivers

The Natural History and Biological Study of Pulmonary Recurrent Respiratory Papillomatosis (pRRP)

Varenicline and Accelerated Transcranial Magnetic Stimulation (TMS) for Quitting Nicotine Use (Pilot Study)

Extracellular RNA Biomarkers of Myotonic Dystrophy

Initial Resuscitation for Acute Kidney Injury in Cirrhosis

Partners Calciphylaxis Biobank

Biomarker Development for Muscular Dystrophies

Improving Health for Older Adults With Pain Through Engagement

Addressing Emotional Distress in Dyads of Persons With a Young Onset Dementia (YOD) and Their Care-partners

Resilient Families Feasibility Trial

Time Restricted Eating (TRE) in Bipolar Disorder

HIPS Feasibility Randomized Controlled Trial

Restor. I-131 Upt. + Selpercatinib in RET F-P RAI-R TC

Training in Evidence-based Treatments in Psycho-Oncology

Optimizing the Diagnostic Approach to Cephalosporin Allergy Testing

Well-being in IBS: Strengths and Happiness (WISH) 2.0

Bronchial NIR Image-guided Resection

Digital Sleep Optimization for Brain Health Outcomes in Older Surgical Patients

Project 4: Ambulatory Biofeedback and Voice Therapy for Patients With Vocal Hyperfunction

Efficacy of Synchronous, Virtual Cognitive Behavioral Therapy for Insomnia Across Phases of Cancer Survivorship

Folfox+Irinotecan+Chemort In Esophageal Cancer

Pilot Study of Health System/Community Partnership for Enhanced Outreach to Prevent Suicide Attempts

Buspirone and Melatonin for Depression Following Traumatic Brain Injury

Eliminating Barriers to Colorectal Cancer Screening Using Rapid Cycle Testing: A Pilot Study

EVOC - EVs in Obesity and Cardiometabolic Disease

Purified Cortrophin® Gel Efficacy and Safety Study of 2 Dose Levels in Patients With Acute Gout Flares

Prospective Screening for Breast Cancer-related Lymphedema

Imaging Histone Deacetylase in the Heart

Targeting Specific Brain Networks to Treat Specific Symptoms in Depression

Immune Response to Percutaneous Hepatic Perfusion With Melphalan for Ocular Melanoma Metastatic to the Liver

Genetic Testing Decision Aid

Sacituzumab Govitecan In TNBC

Precision Biomarkers to Detect Brain Injury in Active-Duty United States Special Operations Forces With Repeated Blast Exposure

45th Multicenter Airway Research Collaboration

Identifying Multidimensional Signatures of Gastric Interoception in Functional Dyspepsia

Change My Story Task Shifted Mental Health Intervention

Romosozumab as an Adjunct to Physiologic Estrogen Replacement in Functional Hypothalamic Amenorrhea

PET/MRI/EEG Imaging Study in Epilepsy

Value of [68Ga]Ga-PSMA-11 PET/MRI in the Assessment of Liver Cirrhosis

Assess Fibrin in Brains With AD/ADRD

Proton or Photon RT for Retroperitoneal Sarcomas

Oxytocin for Weight Loss in Adolescents