NCT06180837 Effect of Sleep Extension on Ceramides in People with Overweight and Obesity
| NCT ID | NCT06180837 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Utah |
| Condition | Lifestyle Factors |
| Study Type | INTERVENTIONAL |
| Enrollment | 70 participants |
| Start Date | 2024-02-12 |
| Primary Completion | 2028-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 70 participants in total. It began in 2024-02-12 with a primary completion date of 2028-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The overall goal is to determine how a sleep extension intervention (increasing time in bed) in individuals who maintain less than 6.5 hours sleep per night affects their plasma ceramides and insulin sensitivity. Participants will undergo a randomized controlled trial, with sleep extension (intervention) and healthy lifestyle (control) groups. The sleep extension is designed to increase participant's time in bed by 2 hours per night. Alternatively, the control group will receive basic health information (e.g., physical activity, goal setting, and nutrition when eating out).
Eligibility Criteria
Inclusion Criteria: 1. Age: 18-45 years old; equal numbers of men and women 2. Body mass index (BMI): 27.5-34.9 kg/m2 3. Sleep Habits: habitual self-reported average total sleep time (TST) \<6.5 hours per night for prior 6 months Exclusion Criteria: 1. Clinically diagnosed sleep disorder or major psychiatric illness 2. Evidence of significant organ dysfunction or disease (e.g., heart disease, kidney disease) 3. Clinically diagnosed diabetes or fasting plasma glucose ≥126 mg/dL or HbA1c ≥6.5% 4. Use of prescription drugs or substances known to influence sleep or glucose metabolism, or anticoagulant medications. 5. Cancer that has been in remission less than 5 years 6. Pregnant/nursing, experiencing menopause or post-menopausal 7. Shift-work: current or history of within last year 8. Weight change: \>10% of body weight over prior six months 9. Current enrollment in weight loss or physical activity program like the Diabetes Prevention Program 10. Currently smoking 11. Alcohol intake\>14 drinks per week or \>3 drinks per day
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06180837 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 45 Years, studying Lifestyle Factors. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06180837 currently recruiting?
Yes, NCT06180837 is actively recruiting participants. Contact the research team at christopher.depner@utah.edu for enrollment information.
Where is the NCT06180837 trial being conducted?
This trial is being conducted at Salt Lake City, United States.
Who is sponsoring the NCT06180837 clinical trial?
NCT06180837 is sponsored by University of Utah. The trial plans to enroll 70 participants.