NCT06168162 Effect of Individualized PEEP on Postoperative Pulmonary Complication in Bariatrics
| NCT ID | NCT06168162 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Ain Shams University |
| Condition | Mechanical Ventilation Pressure High |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2023-10-01 |
| Primary Completion | 2025-04-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2023-10-01 with a primary completion date of 2025-04-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Ventilation with low tidal volume and high PEEP (positive end expiratory pressure) has been shown to improve oxygenation in patients with ARDS (acute respiratory distress syndrome). In obese patients undergoing laparoscopic bariatric surgeries, the risk of postoperative pulmonary complications (PPCs) increases significantly with general anesthesia. Previous studies have shown that protective lung ventilation strategies could improve intraoperative oxygenation and lung mechanics. In this study would compare the effect of optimum individualized high PEEP versus standard PEEP - on postoperative pulmonary complications
Eligibility Criteria
Inclusion Criteria: * Patients were eligible for participation if the met the following criteria * Age between 18 and 60 years old. * Body mass index \> 40 * Laparoscopic bariatric elective surgery under general anesthesia. * ARISCAT (Assess Respiratory Risk in Surgical Patients in Catalonia) score ≥ 45 . ARISCAT score is a clinically practical seven-factor scoring system to assess the risk of a composite PPC. Exclusion Criteria: * Previous lung surgery * ASA status III or IV. * Moderate to severe obstructive or restrictive lung disease . * Persistant intraoperative hemodynamic instability . * Need for postoperative mechanical ventilation
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06168162 clinical trial?
This trial is open to participants of all sexes, aged 16 Years or older, studying Mechanical Ventilation Pressure High. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06168162 currently recruiting?
Yes, NCT06168162 is actively recruiting participants. Contact the research team at w.z.selima@med.asu.edu.eg for enrollment information.
Where is the NCT06168162 trial being conducted?
This trial is being conducted at Cairo, Egypt.
Who is sponsoring the NCT06168162 clinical trial?
NCT06168162 is sponsored by Ain Shams University. The trial plans to enroll 50 participants.