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Recruiting NCT05336760

NCT05336760 Dysphagia, QoL and Attitudes Towards PEG in ALS Patients

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Clinical Trial Summary
NCT ID NCT05336760
Status Recruiting
Phase
Sponsor University Rehabilitation Institute, Republic of Slovenia
Condition Amyotrophic Lateral Sclerosis
Study Type OBSERVATIONAL
Enrollment 60 participants
Start Date 2023-01-01
Primary Completion 2026-09-30

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age N/A
Study Type OBSERVATIONAL
Interventions
Iowa Oral Performance Instrument (IOPI)Mann Assessment of Swallowing Ability (MASA)Fiberoptic Endoscopic Evaluation of Swallowing

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 60 participants in total. It began in 2023-01-01 with a primary completion date of 2026-09-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

In Amyotrophic Lateral Sclerosis, dysphagia has a high incidence. With deterioration of swallowing function, percutaneous endoscopic gastrostomy (PEG) tube is recommended to ensure sufficient and safe oral intake. Dysphagia and PEG placement alter quality of life (QoL). However, QoL and attitudes toward PEG remain largely unexplored. The purpose of this study is to monitor the swallowing function in relationship to QoL and attitudes toward PEG tube insertion and feeding.

Eligibility Criteria

Inclusion Criteria for patients: * 18 years of age or older * diagnosis of ALS * follow-up at University Medical Centre Ljubljana, Division of Neurophysiology, every 3 months * be able to visit the study site for in-person procedures every 3 months Inclusion Criteria for relatives: * at least 18 years of age Exclusion Criteria for patients: * co-existing illness or disorder that could influence the swallowing function independently of the ALS diagnosis * clinically significant cognitive deterioration or dementia at enrollment, as determined by the ALS study neurologist Exclusion criteria for relatives: * signs of probable cognitive deterioration or dementia at enrollment

Contact & Investigator

Central Contact

Metka Moharić, MD, PhD

✉ metka.moharic@ir-rs.si

📞 +386 1 4758441

Principal Investigator

Blaž Koritnik, MD, PhD

PRINCIPAL INVESTIGATOR

University Medical Centre Ljubljana

Frequently Asked Questions

Who can join the NCT05336760 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, studying Amyotrophic Lateral Sclerosis. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT05336760 currently recruiting?

Yes, NCT05336760 is actively recruiting participants. Contact the research team at metka.moharic@ir-rs.si for enrollment information.

Where is the NCT05336760 trial being conducted?

This trial is being conducted at Ljubljana, Slovenia.

Who is sponsoring the NCT05336760 clinical trial?

NCT05336760 is sponsored by University Rehabilitation Institute, Republic of Slovenia. The principal investigator is Blaž Koritnik, MD, PhD at University Medical Centre Ljubljana. The trial plans to enroll 60 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology