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amyotrophic lateral sclerosis

Total Trials
13
Recruiting Now
13
Trial Phases
Phase 2, Phase 1, Phase 1, Phase 2

ClinicalMetric tracks all active clinical trials for amyotrophic lateral sclerosis sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — amyotrophic lateral sclerosis Clinical Trials

How many clinical trials are currently recruiting for amyotrophic lateral sclerosis?
ClinicalMetric currently tracks 13 actively recruiting clinical trials for amyotrophic lateral sclerosis, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 13. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for amyotrophic lateral sclerosis?
amyotrophic lateral sclerosis research spans Phase 1 (2 trials), Phase 2 (3 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a amyotrophic lateral sclerosis clinical trial?
Eligibility criteria for amyotrophic lateral sclerosis trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
2
Phase 2
3
Top Sponsors
Haukeland University Hospital 1 trial
Shanghai StairMed Technology Co., Ltd. 1 trial
Beth Israel Deaconess Medical Center 1 trial
Istituto Auxologico Italiano 1 trial
Centre Hospitalier Universitaire de Liege 1 trial

Recruiting Clinical Trials

NCT05095571
Recruiting
A Trial of Nicotinamide/Pterostilbene Supplement in ALS: The NO-ALS Extension Study
Enrollment
300 pts
Location
Norway
Sponsor
Haukeland University Hospital
View Trial →
NCT06829212
Recruiting
Research on Wireless Brain Implant System for General Control of External Devices
Enrollment
4 pts
Location
China
Sponsor
Shanghai StairMed Technology C...
View Trial →
NCT06491732
Recruiting
EIM Via the Myolex mScan as an ALS Biomarker
Enrollment
80 pts
Location
United States
Sponsor
Beth Israel Deaconess Medical ...
View Trial →
NCT07302321
Recruiting
Needs of ALS Patients With C9orf72 Mutation and Their Caregivers
Enrollment
208 pts
Location
Italy
Sponsor
Istituto Auxologico Italiano
View Trial →
NCT06228001
Recruiting
Holter of Movement in Patients With Amyotrophic Lateral Sclerosis.
Enrollment
30 pts
Location
Belgium, Egypt
Sponsor
Centre Hospitalier Universitai...
View Trial →
NCT06344260 Phase 2
Recruiting
Neural Stem Cell Treatment for Amyotrophic Lateral Sclerosis (STEMALS)
Enrollment
30 pts
Location
Italy
Sponsor
Casa Sollievo della Sofferenza...
View Trial →
NCT06578195
Recruiting
ASSESS ALL ALS Study
Enrollment
2,000 pts
Location
United States, Puert...
Sponsor
St. Joseph's Hospital and Medi...
View Trial →
NCT07571174 Phase 1
Recruiting
A Substudy of LY4256984 in Participants With Sporadic Amyotrophic Lateral Sclerosis
Enrollment
32 pts
Location
Belgium, Canada, Ger...
Sponsor
Eli Lilly and Company
View Trial →
NCT06527222 Phase 2
Recruiting
A Study of Ranolazine in ALS
Enrollment
72 pts
Location
United States
Sponsor
Swathy Chandrashekhar, MBBS
View Trial →
NCT05983211
Recruiting
Quantitative and Repetitive TMS in ALS - Recruiting for Stage 2
Enrollment
15 pts
Location
Canada
Sponsor
Sunnybrook Health Sciences Cen...
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NCT05724173
Recruiting
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia
Enrollment
3 pts
Location
United States
Sponsor
Leigh R. Hochberg, MD, PhD.
View Trial →
NCT06598202 Phase 1, Phase 2
Recruiting
Exploring Nasal Drop Therapy With Small Extracellular Vesicles for ALS
Enrollment
38 pts
Location
China
Sponsor
Xuanwu Hospital, Beijing
View Trial →
NCT05137665
Recruiting
Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures
Enrollment
1,000 pts
Location
United States, Colom...
Sponsor
Target ALS Foundation, Inc.
View Trial →

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology