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Recruiting NCT06690385

NCT06690385 DEPRECAP: Lung Cancer Screening Programme by LDCT for Patients With COPD or Emphysema.

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Clinical Trial Summary
NCT ID NCT06690385
Status Recruiting
Phase
Sponsor Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Condition Lung Cancer
Study Type OBSERVATIONAL
Enrollment 1,998 participants
Start Date 2014-01-14
Primary Completion 2024-11-13

Eligibility & Interventions

Sex All sexes
Min Age 55 Years
Max Age 75 Years
Study Type OBSERVATIONAL

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.

This trial targets 1,998 participants in total. It began in 2014-01-14 with a primary completion date of 2024-11-13.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

The DEPRECAP (Early detection of lung cancer) study is an ongoing, prospective, longitudinal, multicenter lung cancer screening program that recruited individuals with COPD or emphysema from the pulmonary clinics of Fundación Jiménez Díaz University Hospital and Villalba General Hospital, in Madrid, Spain. The aim of this observational study is to determine the scientific evidence needed to study the benefit and potential effects of lung cancer screening in this group of patients and to determine the long-term effects of the intervention in reducing the high mortality rates associated with late-stage lung cancer diagnosis in a very high-risk population, to address under-diagnosis of COPD and to promote smoking cessation. This leads to the creation of a registry with clinical, radiological, functional data and biological samples for future studies in this cohort of patients to provide the scientific evidence needed to study the benefit and potential effects of screening for lung cancer and other tobacco-related pathologies diagnosed by Low-dose CT (LDCT)

Eligibility Criteria

Inclusion Criteria: * Current or former smokers (\>15 years of abstinence) with a cumulative smoking exposure of \> 30 pack-years * Diagnosis of COPD according to the GOLD guidelines and/or emphysema identified by LDCT and/or a carbon monoxide diffusing capacity (DLCO) lower than 80% of predicted (as per the Global Lung Function Initiative (GLI) equations) Exclusion Criteria: * Individuals with a recent history of cancer (except non-melanoma skin cancer or carcinoma in situ) as well as those with other medical conditions that posed a significant risk of death were excluded from the study.

Contact & Investigator

Central Contact

Carolina Gotera, MD

✉ carolina.gotera@fjd.es

📞 +34 915504800

Principal Investigator

Carolina Gotera, MD

PRINCIPAL INVESTIGATOR

Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz

Frequently Asked Questions

Who can join the NCT06690385 clinical trial?

This trial is open to participants of all sexes, aged 55 Years or older, up to 75 Years, studying Lung Cancer. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT06690385 currently recruiting?

Yes, NCT06690385 is actively recruiting participants. Contact the research team at carolina.gotera@fjd.es for enrollment information.

Where is the NCT06690385 trial being conducted?

This trial is being conducted at Madrid, Spain, Madrid, Spain.

Who is sponsoring the NCT06690385 clinical trial?

NCT06690385 is sponsored by Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz. The principal investigator is Carolina Gotera, MD at Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz. The trial plans to enroll 1,998 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology