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Recruiting NCT06788886

Breathing Practice for Brain and Mental Health in Cancer and Neurodegenerative Diseases

Trial Parameters

Condition Malignant Brain Neoplasm
Sponsor Mayo Clinic
Study Type INTERVENTIONAL
Phase N/A
Enrollment 147
Sex ALL
Min Age 18 Years
Max Age 85 Years
Start Date 2025-02-05
Completion 2027-01-18
Interventions
Biospecimen CollectionExercise InterventionMagnetic Resonance Imaging

Brief Summary

This clinical trial studies the effect of respiratory training for enhancing brain and mental health among patients with multiple sclerosis (MS) and cancer (along with their caregivers). The relationship between respiration, cardiovascular effects in the brain, mental health, and neurophysiological mechanisms are significant for patient populations facing complex health challenges, such as those with cancer and neurodegenerative disease, and their caregivers. By measuring oxygen delivery to brain tissues and cerebrospinal fluid flow, this trial may help researchers investigate the potential benefits of respiratory training for patients with MS and cancer and their caregivers.

Eligibility Criteria

Inclusion Criteria: * STUDY 1: Participants must be physically fit enough to perform light exercise. * STUDY 1: Should read and understand English well enough to consent, complete measures, and follow instructions. * STUDY 1: Must have access to a smartphone or tablet. * STUDY 2: Participants must be physically fit enough to perform light exercise. * STUDY 2: Cancer patients may have prostate cancer, neuroendocrine tumor, or brain cancer in any stage. * STUDY 2: The main focus is on pairs of cancer patients and their respective caregivers, but individual cancer patients or individual caregivers are also acceptable. * STUDY 2: Participants should read and understand English well enough to consent, complete measures, and follow instructions. * STUDY 2: They also must have access to a smartphone or tablet. * STUDY 3: Participants must be physically fit enough to perform light exercise. * STUDY 3: The patient should have multiple sclerosis. * STUDY 3: Participants should read and understan

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