NCT05756257 Blood Pressure Variability and Ischemic Stroke Outcome
| NCT ID | NCT05756257 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Yale University |
| Condition | Acute Ischemic Stroke |
| Study Type | OBSERVATIONAL |
| Enrollment | 150 participants |
| Start Date | 2024-07-15 |
| Primary Completion | 2026-07-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 150 participants in total. It began in 2024-07-15 with a primary completion date of 2026-07-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to evaluate the role of blood pressure (BPV) variability in patients suffering from acute ischemic stroke. The main questions it aims to answer are: 1. To determine the association of BPV with functional/cognitive outcome after ischemic stroke. 2. To determine a pathophysiologic mechanism of BPV's deleterious effect on functional outcome. 3. To evaluate potential treatment targets to pharmacologically reduce BPV after ischemic stroke.
Eligibility Criteria
Inclusion Criteria: * Ischemic stroke according to the American Heart Association (AHA) definition and either: 1. CT or MRI showing ischemic stroke in the anterior circulation (frontal, parietal or superior temporal lobes), or 2. Occlusion of the internal carotid, middle cerebral or anterior cerebral arteries on computed tomography angiography (CTA) or magnetic resonance angiography (MRA) Onset of ischemic stroke within 48 hours and able to get baseline pMRI within 72 hours of arrival 4\) NIH Stroke Scale ≥ 4 at time of enrollment Exclusion Criteria: * Pre-morbid mRS ≥3 * Predicted hospital system admission \<72 hours * Pacemaker or other MRI contraindications per American College of Radiology guidelines
Contact & Investigator
Adam de Havenon, MD
PRINCIPAL INVESTIGATOR
Yale University
Frequently Asked Questions
Who can join the NCT05756257 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Acute Ischemic Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05756257 currently recruiting?
Yes, NCT05756257 is actively recruiting participants. Contact the research team at adam.dehavenon@yale.edu for enrollment information.
Where is the NCT05756257 trial being conducted?
This trial is being conducted at New Haven, United States, Chicago, United States, Boston, United States.
Who is sponsoring the NCT05756257 clinical trial?
NCT05756257 is sponsored by Yale University. The principal investigator is Adam de Havenon, MD at Yale University. The trial plans to enroll 150 participants.
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