NCT07603583 Assessment of Heart Rate Variability for Predicting Obstructive Sleep Apnea in Patients With Hypertension
| NCT ID | NCT07603583 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Kaohsiung Armed Forces General Hospital |
| Condition | Obstructive Sleep Apnea |
| Study Type | OBSERVATIONAL |
| Enrollment | 100 participants |
| Start Date | 2026-04-30 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 100 participants in total. It began in 2026-04-30 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to investigate the relationship between hypertension and obstructive sleep apnea (OSA) using heart rate variability (HRV) as a non-invasive biomarker of autonomic nervous system function. Hypertensive patients at high risk for OSA will undergo 24-hour Holter electrocardiogram monitoring to assess HRV parameters, along with overnight polysomnography (PSG) to determine OSA severity. The study will analyze the association between HRV indices and the apnea-hypopnea index (AHI), and develop predictive models using machine learning techniques. In addition, patients diagnosed with OSA will be followed after treatment, and changes in HRV and blood pressure will be evaluated to assess treatment effects and autonomic function recovery. The results of this study may provide a cost-effective and clinically applicable approach for early detection, risk stratification, and management of OSA in patients with hypertension.
Eligibility Criteria
Inclusion Criteria: * Age 18 to 65 years * Diagnosed hypertension or resistant hypertension * STOP-Bang score ≥3 indicating high risk of obstructive sleep apnea * Willing and able to provide informed consent Exclusion Criteria: * Refusal to undergo HRV monitoring or polysomnography * Unstable medical condition that may interfere with study participation * Inability to comply with study procedures
Contact & Investigator
Yung Kuo Lee, PhD
PRINCIPAL INVESTIGATOR
Kaohsiung Armed Forces General Hospital
Frequently Asked Questions
Who can join the NCT07603583 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Obstructive Sleep Apnea. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07603583 currently recruiting?
Yes, NCT07603583 is actively recruiting participants. Contact the research team at abstyle0204@gmail.com for enrollment information.
Where is the NCT07603583 trial being conducted?
This trial is being conducted at Kaohsiung City, Taiwan.
Who is sponsoring the NCT07603583 clinical trial?
NCT07603583 is sponsored by Kaohsiung Armed Forces General Hospital. The principal investigator is Yung Kuo Lee, PhD at Kaohsiung Armed Forces General Hospital. The trial plans to enroll 100 participants.