NCT04984473 A Study to Evaluate Breathing Muscle Training in Cardiac Rehab
| NCT ID | NCT04984473 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Mayo Clinic |
| Condition | Healthy |
| Study Type | INTERVENTIONAL |
| Enrollment | 42 participants |
| Start Date | 2021-06-01 |
| Primary Completion | 2027-08 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 42 participants in total. It began in 2021-06-01 with a primary completion date of 2027-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study is to understand if breathing muscle training combined with cardiac rehabilitation influences the blood flow and blood pressure response during exercise.
Eligibility Criteria
Inclusion Criteria - Heart Failure Group: * Adult 18 years and older. * English speaking. * Has a qualifying heart failure indication for center-based cardiac rehabilitation. Inclusion Criteria - Healthy Control Group: * Adult 18 years and older. * English speaking. * Absence of pulmonary, cardiovascular, musculoskeletal, neurologic, or orthopedic diseases. Controls will be matched for age and sex. Exclusion Criteria: * HF patients who are unable to engage in a regularly structured exercise training program as part of a clinically indicated center-based outpatient cardiac rehabilitation program. * Participants unable/unwilling to provide informed consent. * Uremia, history of allergy to iodides. Impaired renal function. * Creatinine value greater than 1.3 mg/dL (via clinical record within the past 6 months). * Diagnosis of liver disease.
Contact & Investigator
Joshua Smith, PhD
PRINCIPAL INVESTIGATOR
Mayo Clinic
Frequently Asked Questions
Who can join the NCT04984473 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Healthy. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04984473 currently recruiting?
Yes, NCT04984473 is actively recruiting participants. Contact the research team at bruhn.eric@mayo.edu for enrollment information.
Where is the NCT04984473 trial being conducted?
This trial is being conducted at Rochester, United States.
Who is sponsoring the NCT04984473 clinical trial?
NCT04984473 is sponsored by Mayo Clinic. The principal investigator is Joshua Smith, PhD at Mayo Clinic. The trial plans to enroll 42 participants.