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Recruiting Phase 1 NCT07308236

NCT07308236 A Study to Determine the Metabolism and Excretion of [14C]E2086 in Healthy Male Participants

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Clinical Trial Summary
NCT ID NCT07308236
Status Recruiting
Phase Phase 1
Sponsor Eisai Inc.
Condition Healthy Volunteers
Study Type INTERVENTIONAL
Enrollment 10 participants
Start Date 2025-12-31
Primary Completion 2026-02-23

Trial Parameters

Condition Healthy Volunteers
Sponsor Eisai Inc.
Study Type INTERVENTIONAL
Phase Phase 1
Enrollment 10
Sex MALE
Min Age 18 Years
Max Age 55 Years
Start Date 2025-12-31
Completion 2026-02-23
Interventions
E2086

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Brief Summary

The primary purpose of this study is to determine the metabolism and excretion of \[14C\]E2086 in healthy male participants.

Eligibility Criteria

Inclusion Criteria: 1. Non-smoking and non-vaping, healthy male, age greater than or equal to (\>=) 18 years and less than or equal to (\<=) 55 years old at the time of informed consent 2. Body Mass Index (BMI) \>=18 and less than (\<) 30 kilogram per square meter (kg/m\^2) at Screening 3. Provide written informed consent 4. Willing and able to comply with all aspects of the protocol Exclusion Criteria: 1. Have previously been dosed in more than 2 radiolabeled drug studies in the past 12 months. For participants who have previously been dosed in 2 or more radiolabeled drug studies within the last 12 months, the previous radiolabeled dose must be at least 4 months prior to check-in to the trial site where exposures are known to the investigator, or 6 months prior to check-in to the trial site for a radiolabeled drug trial where exposures are not known to the investigator. The total 12-month exposure from this trial and a maximum of 2 other previous radiolabeled studies must be within th

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