NCT02484885 Xenon-129 Magnetic Resonance Imaging of Healthy Subjects: Hardware and Software Development and Reproducibility
| NCT ID | NCT02484885 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Western University, Canada |
| Condition | Healthy Volunteers |
| Study Type | INTERVENTIONAL |
| Enrollment | 50 participants |
| Start Date | 2011-08 |
| Primary Completion | 2025-08 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 50 participants in total. It began in 2011-08 with a primary completion date of 2025-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Healthy volunteers aged 18-85 will undergo hyperpolarized 129-Xe MRI and pulmonary function testing for the development of tools to assess image signal to noise and reproducibility of spin-density and diffusion-weighted imaging.
Eligibility Criteria
Inclusion Criteria: * able to perform a breath hold for up to 16 sec * BMI between 18 and 40 * stable health on the basis of medical history * smoking history \< 1 pack/year Exclusion Criteria: Patient is, in the opinion of the investigator, mentally or legally incapacitated, preventing informed consent from being obtained, or cannot read or understand the written material. * Subject has a daytime room air oxygen saturation \<90% while lying supine. * Patient is unable to perform spirometry or plethysmography maneuvers * Patient is pregnant * In the investigator's opinion, subject suffers from any physical, psychological or other condition(s) that might prevent performance of the MRI, such as severe claustrophobia. * Subject has an implanted mechanically, electrically or magnetically activated device or any metal in their body which cannot be removed, including but not limited to pacemakers, neurostimulators, biostimulators, implanted insulin pumps, aneurysm clips, bioprosthesis, artificial limb, metallic fragment or foreign body, shunt, surgical staples (including clips or metallic sutures and/or ear implants.)
Contact & Investigator
Grace E Parraga, PhD
PRINCIPAL INVESTIGATOR
Robarts Research Institute, The University of Western Ontario
Frequently Asked Questions
Who can join the NCT02484885 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 85 Years, studying Healthy Volunteers. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT02484885 currently recruiting?
Yes, NCT02484885 is actively recruiting participants. Contact the research team at gparraga@robarts.ca for enrollment information.
Where is the NCT02484885 trial being conducted?
This trial is being conducted at London, Canada.
Who is sponsoring the NCT02484885 clinical trial?
NCT02484885 is sponsored by Western University, Canada. The principal investigator is Grace E Parraga, PhD at Robarts Research Institute, The University of Western Ontario. The trial plans to enroll 50 participants.