NCT07908693 A Novel Treatment for Chronic Low Back Pain Using Multi Angular Isometric Lumbar Exercise: Randomized Clinical Trial.
| NCT ID | NCT07908693 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Hamad Medical Corporation |
| Condition | Nonspecific Low Back Pain |
| Study Type | INTERVENTIONAL |
| Enrollment | 98 participants |
| Start Date | 2025-06-22 |
| Primary Completion | 2027-06-22 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 98 participants in total. It began in 2025-06-22 with a primary completion date of 2027-06-22.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The study aims to evaluate the effectiveness of Multi Angular Isometric Lumbar Exercise (MAILE) in comparison to traditional lumbar stabilization and core stability treatments for managing nonspecific chronic low back pain (NCLBP). MAILE is designed to specifically target the Lumbo-Pelvic Hip complex with the goal of improving pain levels, stability, strength, and overall function. Objectives of the study are to assess several key outcomes: Pain Intensity: Measuring the level of pain experienced by patients. Functional Disability: Evaluating the impact of NCLBP on daily activities and overall function. Functional Stability: Assessing the stability of the Lumbo-Pelvic Hip complex during movement. Muscle Strength: Determining the strength of muscles within the targeted region. By examining these outcomes, the research seeks to determine whether MAILE offers superior benefits and greater cost-efficiency compared to conventional treatments for patients with NCLBP and motor control dysfunction. If successful, MAILE could provide a more effective and economical approach to managing this common and debilitating condition. This Randomized Clinical Trial (RCT) will be conducted across multiple outpatient clinics within the Hamad Medical Corporation (HMC). The study will involve 98 patients diagnosed with non-specific chronic low back pain (NCLBP), who will be randomly assigned to one of two groups: the Multi Angular Isometric Lumbar Exercises (MAILE) group or the Core Stability group. Both groups will follow tailored exercise programs over a three-week period. The MAILE group will focus on exercises designed to enhance lumbar stability and core strength through multi-angular isometric lumbar exercises performed at various angles. These exercises aim to target the deep stabilizing muscles of the lumbar spine, promoting overall spinal stability and reducing pain. The Core Stability group will engage in exercises that emphasize the activation and strengthening of the core muscles, which play a crucial role in maintaining spinal stability and function. The outcomes of this trial will help determine the effectiveness of MAILE compared to traditional core stability exercises in managing NCLBP, potentially guiding future therapeutic strategies.
Eligibility Criteria
Inclusion Criteria: Participants eligible for this study must meet the following criteria: Age between 18-60 years Diagnosed with Nonspecific Chronic Low Back Pain (NCLBP) by an orthopedic doctor, general physician, neurologist, or primary healthcare doctor Low back pain lasting for more than 3 months (pain between T12 and the gluteal fold) Must have had more pain-free days than painful days during the past year Pain located mainly in the lower lumbar region (L4/L5 and/or L5/S1) Presence of positive prone instability test Presence of aberrant movement during motion testing Straight Leg Raise \> 91° BMI between 20-30 Presence of one or more of the following: Pain worsens with sustained end-range movements or positions Lumbar hypermobility on segmental motion assessment Mobility deficits of the thorax and lumbopelvic/hip regions Reduced trunk or pelvic muscle strength and endurance Movement coordination impairments during work, recreational, or daily functional activities Patients must also: Be willing and able to safely participate in an exercise program Have no cognitive impairment limiting participation Exclusion Criteria: Participants will be excluded if they have any of the following: Radiculopathy (confirmed through clinical and neurological assessment) Cauda equina symptoms (e.g., bowel/bladder dysfunction, perianal numbness) Spinal deformities (fracture, infection, tumor) Severe osteoporosis History of lumbar spine surgery Pregnancy Psychiatric illness or cognitive impairment (e.g., dementia) Substance abuse Use of medications: Current anticoagulants or corticosteroids Long-term steroid use (≥7.5 mg for \>6 months) Recent or significant trauma Pain or neurological symptoms during positioning or lever application (unsafe for intervention) Cardiac conditions Cancer Other significant medical conditions, including: Rheumatologic disorders Spinal infections Prior back surgery
Contact & Investigator
Yadulla Syed, MPT Ortho
PRINCIPAL INVESTIGATOR
Hamad Medical Corporation
Frequently Asked Questions
Who can join the NCT07908693 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 60 Years, studying Nonspecific Low Back Pain. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07908693 currently recruiting?
Yes, NCT07908693 is actively recruiting participants. Contact the research team at Ysayed@hamad.qa for enrollment information.
Where is the NCT07908693 trial being conducted?
This trial is being conducted at Doha, Qatar.
Who is sponsoring the NCT07908693 clinical trial?
NCT07908693 is sponsored by Hamad Medical Corporation. The principal investigator is Yadulla Syed, MPT Ortho at Hamad Medical Corporation. The trial plans to enroll 98 participants.