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traumatic brain injury Clinical Trials in United States

Active clinical trials for traumatic brain injury with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.

Active Trials: 22 // Recruiting: 22 Phases: Phase 2, Phase 4 // Updated: Daily
Total Trials
22
Recruiting Now
22
Country
🇺🇸 United States

Active Trials in United States (22)

NCT07176936
Recruiting

Improving Speech in Noise Using Noninvasive Stimulation

Enrollment
55 pts
Country
🇺🇸 United States
University of Florida
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NCT06293300 Phase 2
Recruiting

Understanding and Treating Traumatic Brain Injury (TBI) Associated Photophobia With Botulinum Toxin Type A (BoNT-A)

Enrollment
50 pts
Country
🇺🇸 United States
University of Miami
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NCT04869059
Recruiting

Treating Mild Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation

Enrollment
136 pts
Country
🇺🇸 United States
The University of Texas at Dallas
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NCT05933629
Recruiting

Community-based Implementation of Online EmReg

Enrollment
50 pts
Country
🇺🇸 United States
Icahn School of Medicine at Mount S...
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NCT07635329
Recruiting

Home-based Vision Rehabilitation Guided by Brain Imaging

Enrollment
100 pts
Country
🇺🇸 United States
Georgetown University
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NCT07225101 Phase 4
Recruiting

Evaluation of the Efficacy of STRATAFIX for Neurosurgical Cranial and Spine Procedures

Enrollment
160 pts
Country
🇺🇸 United States
University of Michigan
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NCT05683145
Recruiting

University of Colorado - Restoring Efficient Sleep After TBI

Enrollment
80 pts
Country
🇺🇸 United States
VA Eastern Colorado Health Care Sys...
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NCT05702138 Phase 2
Recruiting

High Intensity Step Training After Traumatic Brain Injury

Enrollment
111 pts
Country
🇺🇸 United States
Craig Hospital
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NCT07357090
Recruiting

Carbon Dioxide Administration and Brain Waste Clearance

Enrollment
200 pts
Country
🇺🇸 United States
Andrew Mayer
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NCT06062628 EARLY_Phase 1
Recruiting

Ketamine in Severe Traumatic Brain Injury

Enrollment
10 pts
Country
🇺🇸 United States
University of Texas Southwestern Me...
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NCT06494319
Recruiting

Development Of a Virtual Stress Inoculation Training (SIT) Platform and Mobile Health App

Enrollment
20 pts
Country
🇺🇸 United States
The University of Texas Health Scie...
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NCT04349852
Recruiting

Verbal Working Memory and Attention Remediation for Adults With Traumatic Brain Injury.

Enrollment
150 pts
Country
🇺🇸 United States
NYU Langone Health
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NCT06848140
Recruiting

Using Non-invasive Brain Stimulation to Treat Word Finding Difficulty in Chronic Traumatic Brain Injury

Enrollment
24 pts
Country
🇺🇸 United States
Beth Israel Deaconess Medical Cente...
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NCT06028334
Recruiting

GetUp&Go: A Randomized Controlled Trial of an Intervention to Enhance Physical Activity After TBI

Enrollment
70 pts
Country
🇺🇸 United States
Albert Einstein Healthcare Network
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NCT05725993
Recruiting

Longitudinal Assessment of Traumatic Microvascular Injury-2

Enrollment
110 pts
Country
🇺🇸 United States
University of Pennsylvania
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NCT03233646
Recruiting

Retinal Imaging in Neurodegenerative Disease

Enrollment
2,000 pts
Country
🇺🇸 United States
Duke University
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NCT07624825
Recruiting

Emotional Awareness Therapy Study

Enrollment
48 pts
Country
🇺🇸 United States
Hackensack Meridian Health
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NCT06589362
Recruiting

Noninvasive Vagal Nerve Stimulation and Cognitive Rehabilitation

Enrollment
60 pts
Country
🇺🇸 United States
Shirley Ryan AbilityLab
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NCT06828107
Recruiting

A Study to Evaluate the SENSE Device's Ability to Detect TBI

Enrollment
150 pts
Country
🇺🇸 United States
Sense Diagnostics, LLC
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NCT03990909
Recruiting

Pilot Study of BCAA on Sleep

Enrollment
300 pts
Country
🇺🇸 United States
Portland VA Medical Center
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NCT06956404
Recruiting

tPBM in Older Adults With Traumatic Brain Injury

Enrollment
70 pts
Country
🇺🇸 United States
NYU Langone Health
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NCT05628207
Recruiting

Evaluation of the SCALED (SCaling AcceptabLE cDs)

Enrollment
15,000 pts
Country
🇺🇸 United States
University of Minnesota
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Frequently Asked Questions

How many traumatic brain injury clinical trials are active in United States?
There are currently 22 active clinical trials for traumatic brain injury with sites in United States, of which 22 are actively recruiting patients.
How can I join a traumatic brain injury clinical trial in United States?
To join a traumatic brain injury clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are traumatic brain injury trials in United States?
Active traumatic brain injury trials in United States span Phase 2, Phase 4, EARLY_Phase 1. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology