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Recruiting NCT03990909

NCT03990909 Pilot Study of BCAA on Sleep

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Clinical Trial Summary
NCT ID NCT03990909
Status Recruiting
Phase
Sponsor Portland VA Medical Center
Condition Sleep Disorder
Study Type INTERVENTIONAL
Enrollment 300 participants
Start Date 2019-03-01
Primary Completion 2025-12-01

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 89 Years
Study Type INTERVENTIONAL
Interventions
Branched Chain Amino AcidsRice ProteinMicrocrystalline Cellulose

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 300 participants in total. It began in 2019-03-01 with a primary completion date of 2025-12-01.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Individuals will be recruited from the VA Portland Health Care System and the community affiliated with Oregon Health \& Science University. Traumatic brain injury status will be assessed as a contributing factor. Subjects will be randomized to one of 3 groups (BCAA or one of 2 placebo conditions) and instructed to consume study product twice daily for 21 days. Self-report questionnaires, wrist actigraphy, pressure pain testing, and cognitive function will be assessed pre and post the experimental period.

Eligibility Criteria

Inclusion Criteria: * Veteran * English Speaking * Accessible via phone * Sleep problems Exclusion Criteria: * Decisional impairment * Nickel allergy * Maple syrup urine disease or family history of disease * Allergy to sucralose * Currently taking BCAAs

Contact & Investigator

Central Contact

Miranda M Lim, MD, PhD

✉ lmir@ohsu.edu

📞 503-220-8262

Principal Investigator

Miranda M Lim, MD, PhD

PRINCIPAL INVESTIGATOR

Portland VA Medical Center

Frequently Asked Questions

Who can join the NCT03990909 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 89 Years, studying Sleep Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT03990909 currently recruiting?

Yes, NCT03990909 is actively recruiting participants. Contact the research team at lmir@ohsu.edu for enrollment information.

Where is the NCT03990909 trial being conducted?

This trial is being conducted at Portland, United States.

Who is sponsoring the NCT03990909 clinical trial?

NCT03990909 is sponsored by Portland VA Medical Center. The principal investigator is Miranda M Lim, MD, PhD at Portland VA Medical Center. The trial plans to enroll 300 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology