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Recruiting NCT06848140

Using Non-invasive Brain Stimulation to Treat Word Finding Difficulty in Chronic Traumatic Brain Injury

Trial Parameters

Condition Traumatic Brain Injury
Sponsor Beth Israel Deaconess Medical Center
Study Type INTERVENTIONAL
Phase N/A
Enrollment 24
Sex ALL
Min Age 18 Years
Max Age 85 Years
Start Date 2025-10-01
Completion 2028-04-30
Interventions
Active Transcranial direct current stimulationSham Transcranial direct current stimulation

Brief Summary

The purpose of this study is to learn more about how brain stimulation affects word finding problems in people who have a traumatic brain injury (TBI). The type of brain stimulation used is called transcranial direct current stimulation (tDCS). tDCS delivers low levels of electric current to the brain and high definition tDCS (HD-tDCS) delivers the current with multiple electrodes on the scalp. This current is delivered with HD-tDCS to parts of the brain that may help with remembering things. The investigators hope that this can help to improve word finding and memory problems in people with TBI.

Eligibility Criteria

Inclusion Criteria: * Age between 18 and 85 * Fluent in speaking and reading English * Able to provide informed consent * Has a TBI at least one year prior to enrollment and not related to military experience * Has a confirmation of verbal retrieval difficulties as measured by the Verbal Retrieval Difficulty Interview questions Exclusion Criteria: * Lifetime major or active neurologic conditions (e.g., stroke, epilepsy, brain tumor, dementia, seizure occurrence less than one year ago) * Lifetime major or active cardiovascular conditions (e.g., cardiac arrythmia, heart failure, heart attack) * Current substance use disorder * Lifetime major psychiatric disorders (e.g., schizophrenia, bipolar disorder) * Severe depression at the time of enrollment (BDI-II \>= 29) or psychiatric ER visits or hospitalization less than 6 months ago prior to enrollment * Current sensory (e.g., blind, deaf) or physical (e.g., severe motor weakness) impairment that interferes with testing * Contraindications f

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