🇺🇸 United States Country × Condition
depression Clinical Trials in United States
Active clinical trials for depression with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.
Active Trials: 37 // Recruiting: 37 Phases: Phase 2, Phase 4 // Updated: Daily
Total Trials
37
Recruiting Now
37
Country
🇺🇸 United States
Active Trials in United States (37)
NCT06901687 Phase 2
Recruiting
Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosis (MS)
Enrollment
170 pts
Country
🇺🇸 United States
NYU Langone Health
View Trial → NCT06817993
Recruiting
Teen Brain Online II: Understanding How Social Media Affects the Teen Brain
Enrollment
60 pts
Country
🇺🇸 United States
University of Pittsburgh
View Trial → NCT07478393
Recruiting
Readiness and Progress in Emotion Regulation Therapy
Enrollment
36 pts
Country
🇺🇸 United States
Teachers College, Columbia Universi...
View Trial → NCT06400121 Phase 2
Recruiting
Apimostinel + Automated Neurocognitive Training for Depression
Enrollment
150 pts
Country
🇺🇸 United States
Rebecca Price
View Trial → NCT06073886 Phase 2
Recruiting
Personalized Brain Stimulation to Treat Chronic Concussive Symptoms
Enrollment
75 pts
Country
🇺🇸 United States
University of California, Los Angel...
View Trial → NCT06903819 Phase 4
Recruiting
Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients
Enrollment
90 pts
Country
🇺🇸 United States
Texas Tech University Health Scienc...
View Trial → NCT02604277
Recruiting
Suicidal Behavior in Patients Diagnosed With Bipolar Disorder
Enrollment
130 pts
Country
🇺🇸 United States
Emory University
View Trial → NCT06266611 Phase 2
Recruiting
Cannabis for Palliative Care in Cancer
Enrollment
185 pts
Country
🇺🇸 United States
University of Colorado, Boulder
View Trial → NCT06556589
Recruiting
Collaborative Care for Treatment of Depression and Anxiety
Enrollment
200 pts
Country
🇺🇸 United States
Kaiser Permanente
View Trial → NCT05826860
Recruiting
Storytelling and Mindfulness for Graduate Student Wellbeing
Enrollment
20 pts
Country
🇺🇸 United States
University of Wisconsin, Madison
View Trial → NCT06876129 Phase 1
Recruiting
Pharmacologic Augmentation of TMS for Depression With D-serine
Enrollment
60 pts
Country
🇺🇸 United States
Mclean Hospital
View Trial → NCT06512194 Phase 2
Recruiting
Investigation to Understand and Optimize Psilocybin
Enrollment
141 pts
Country
🇺🇸 United States
Charles Raison
View Trial → NCT06597695 Phase 1, Phase 2
Recruiting
A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression
Enrollment
10 pts
Country
🇺🇸 United States
Juliana Zambrano, MD, MPH
View Trial → NCT07129070
Recruiting
Just-in-Time Training for Youth Mentors
Enrollment
118 pts
Country
🇺🇸 United States
University of Minnesota
View Trial → NCT05754151
Recruiting
Mobile CBT for Middle Aged and Older Adults
Enrollment
60 pts
Country
🇺🇸 United States
Weill Medical College of Cornell Un...
View Trial → NCT06827951
Recruiting
Potential Benefits of Parent Child Interaction Therapy (PCIT)
Enrollment
80 pts
Country
🇺🇸 United States
University of Florida
View Trial → NCT05489042
Recruiting
Functional Connectivity Alterations in Suicidal Patients Among Opioid Users
Enrollment
80 pts
Country
🇺🇸 United States
Baylor College of Medicine
View Trial → NCT06569303
Recruiting
Filipino Family Health Initiative 1.0
Enrollment
500 pts
Country
🇺🇸 United States
Kaiser Permanente
View Trial → NCT06030154
Recruiting
Amplification of Positivity for Alcohol Use
Enrollment
100 pts
Country
🇺🇸 United States
Laureate Institute for Brain Resear...
View Trial → NCT05942469
Recruiting
Fostering Optimal Regulation of Emotion for Prevention of Secondary Trauma (FOREST)
Enrollment
100 pts
Country
🇺🇸 United States
Northwestern University
View Trial → NCT06574035
Recruiting
Michigan Men's Diabetes Project III(MenDIII): Mind and Motion
Enrollment
80 pts
Country
🇺🇸 United States
University of Michigan
View Trial → NCT06735885
Recruiting
fMRI Neurofeedback With Matter Neuroscience App
Enrollment
240 pts
Country
🇺🇸 United States
Stanford University
View Trial → NCT05294991
Recruiting
Wellness App for Sleep Disturbance in Hematological Cancer Patients
Enrollment
276 pts
Country
🇺🇸 United States
The University of Texas Health Scie...
View Trial → NCT06094088
Recruiting
Researching Heat and Yoga for Mood Enhancement
Enrollment
120 pts
Country
🇺🇸 United States
Massachusetts General Hospital
View Trial → NCT06623981
Recruiting
The Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic
Enrollment
60 pts
Country
🇺🇸 United States
Children's National Research Instit...
View Trial → NCT07073963
Recruiting
Virtual Patient Groups for Sarcoidosis Associated Fatigue
Enrollment
100 pts
Country
🇺🇸 United States
The Cleveland Clinic
View Trial → NCT06085937 Phase 1
Recruiting
Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department
Enrollment
50 pts
Country
🇺🇸 United States
Lindsay Maguire, MD
View Trial → NCT04426461
Recruiting
Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome (AAC-BeT)
Enrollment
220 pts
Country
🇺🇸 United States
Laureate Institute for Brain Resear...
View Trial → NCT04713722
Recruiting
Early Life Stress and Depression: Molecular and Functional Imaging
Enrollment
160 pts
Country
🇺🇸 United States
Mclean Hospital
View Trial → NCT05965245
Recruiting
Suubi-Mhealth: A Mobile Health Intervention to Address Depression Among Youth
Enrollment
278 pts
Country
🇺🇸 United States
Washington University School of Med...
View Trial → NCT06500780
Recruiting
Equipping Patients Using Interventions for Pain and Depression
Enrollment
304 pts
Country
🇺🇸 United States
Indiana University
View Trial → NCT06963463
Recruiting
Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)
Enrollment
90 pts
Country
🇺🇸 United States
University of Pittsburgh
View Trial → NCT05081596
Recruiting
A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD
Enrollment
100 pts
Country
🇺🇸 United States
Weill Medical College of Cornell Un...
View Trial → NCT06576076
Recruiting
Cannabis, Linked Emotions, and Adolescent Risk Study
Enrollment
200 pts
Country
🇺🇸 United States
Massachusetts General Hospital
View Trial → NCT05474846 Phase 2, Phase 3
Recruiting
Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer
Enrollment
188 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
View Trial → NCT06839859 Phase 2
Recruiting
Family Acceptance Project Online (Pilot RCT)
Enrollment
180 pts
Country
🇺🇸 United States
University of Michigan
View Trial → NCT06898788 EARLY_Phase 1
Recruiting
Probiotic Administration for Adolescent Depression
Enrollment
77 pts
Country
🇺🇸 United States
University of California, San Franc...
View Trial → Frequently Asked Questions
How many depression clinical trials are active in United States?
There are currently 37 active clinical trials for depression with sites in United States, of which 37 are actively recruiting patients.
How can I join a depression clinical trial in United States?
To join a depression clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are depression trials in United States?
Active depression trials in United States span Phase 2, Phase 4, Phase 1, Phase 1, Phase 2, Phase 2, Phase 3, EARLY_Phase 1. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.