ClinicalMetric / Countries / United States / depression
← 🇺🇸 United States Trials
🇺🇸 United States Country × Condition

depression Clinical Trials in United States

Active clinical trials for depression with research sites in United States. All data sourced live from ClinicalTrials.gov — updated daily.

Active Trials: 37 // Recruiting: 37 Phases: Phase 2, Phase 4 // Updated: Daily
Total Trials
37
Recruiting Now
37
Country
🇺🇸 United States

Active Trials in United States (37)

NCT06901687 Phase 2
Recruiting

Home-Based Transcranial Direct Current Stimulation (tDCS) for Depression in Multiple Sclerosis (MS)

Enrollment
170 pts
Country
🇺🇸 United States
NYU Langone Health
View Trial →
NCT06817993
Recruiting

Teen Brain Online II: Understanding How Social Media Affects the Teen Brain

Enrollment
60 pts
Country
🇺🇸 United States
University of Pittsburgh
View Trial →
NCT07478393
Recruiting

Readiness and Progress in Emotion Regulation Therapy

Enrollment
36 pts
Country
🇺🇸 United States
Teachers College, Columbia Universi...
View Trial →
NCT06400121 Phase 2
Recruiting

Apimostinel + Automated Neurocognitive Training for Depression

Enrollment
150 pts
Country
🇺🇸 United States
Rebecca Price
View Trial →
NCT06073886 Phase 2
Recruiting

Personalized Brain Stimulation to Treat Chronic Concussive Symptoms

Enrollment
75 pts
Country
🇺🇸 United States
University of California, Los Angel...
View Trial →
NCT06903819 Phase 4
Recruiting

Ketamine for Pain, Opioid Use, and Mental Health in Orthopedic Trauma Patients

Enrollment
90 pts
Country
🇺🇸 United States
Texas Tech University Health Scienc...
View Trial →
NCT02604277
Recruiting

Suicidal Behavior in Patients Diagnosed With Bipolar Disorder

Enrollment
130 pts
Country
🇺🇸 United States
Emory University
View Trial →
NCT06266611 Phase 2
Recruiting

Cannabis for Palliative Care in Cancer

Enrollment
185 pts
Country
🇺🇸 United States
University of Colorado, Boulder
View Trial →
NCT06556589
Recruiting

Collaborative Care for Treatment of Depression and Anxiety

Enrollment
200 pts
Country
🇺🇸 United States
Kaiser Permanente
View Trial →
NCT05826860
Recruiting

Storytelling and Mindfulness for Graduate Student Wellbeing

Enrollment
20 pts
Country
🇺🇸 United States
University of Wisconsin, Madison
View Trial →
NCT06876129 Phase 1
Recruiting

Pharmacologic Augmentation of TMS for Depression With D-serine

Enrollment
60 pts
Country
🇺🇸 United States
Mclean Hospital
View Trial →
NCT06512194 Phase 2
Recruiting

Investigation to Understand and Optimize Psilocybin

Enrollment
141 pts
Country
🇺🇸 United States
Charles Raison
View Trial →
NCT06597695 Phase 1, Phase 2
Recruiting

A Ketamine-assisted Group Therapy Intervention for Spanish-speaking Adults With Depression

Enrollment
10 pts
Country
🇺🇸 United States
Juliana Zambrano, MD, MPH
View Trial →
NCT07129070
Recruiting

Just-in-Time Training for Youth Mentors

Enrollment
118 pts
Country
🇺🇸 United States
University of Minnesota
View Trial →
NCT05754151
Recruiting

Mobile CBT for Middle Aged and Older Adults

Enrollment
60 pts
Country
🇺🇸 United States
Weill Medical College of Cornell Un...
View Trial →
NCT06827951
Recruiting

Potential Benefits of Parent Child Interaction Therapy (PCIT)

Enrollment
80 pts
Country
🇺🇸 United States
University of Florida
View Trial →
NCT05489042
Recruiting

Functional Connectivity Alterations in Suicidal Patients Among Opioid Users

Enrollment
80 pts
Country
🇺🇸 United States
Baylor College of Medicine
View Trial →
NCT06569303
Recruiting

Filipino Family Health Initiative 1.0

Enrollment
500 pts
Country
🇺🇸 United States
Kaiser Permanente
View Trial →
NCT06030154
Recruiting

Amplification of Positivity for Alcohol Use

Enrollment
100 pts
Country
🇺🇸 United States
Laureate Institute for Brain Resear...
View Trial →
NCT05942469
Recruiting

Fostering Optimal Regulation of Emotion for Prevention of Secondary Trauma (FOREST)

Enrollment
100 pts
Country
🇺🇸 United States
Northwestern University
View Trial →
NCT06574035
Recruiting

Michigan Men's Diabetes Project III(MenDIII): Mind and Motion

Enrollment
80 pts
Country
🇺🇸 United States
University of Michigan
View Trial →
NCT06735885
Recruiting

fMRI Neurofeedback With Matter Neuroscience App

Enrollment
240 pts
Country
🇺🇸 United States
Stanford University
View Trial →
NCT05294991
Recruiting

Wellness App for Sleep Disturbance in Hematological Cancer Patients

Enrollment
276 pts
Country
🇺🇸 United States
The University of Texas Health Scie...
View Trial →
NCT06094088
Recruiting

Researching Heat and Yoga for Mood Enhancement

Enrollment
120 pts
Country
🇺🇸 United States
Massachusetts General Hospital
View Trial →
NCT06623981
Recruiting

The Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic

Enrollment
60 pts
Country
🇺🇸 United States
Children's National Research Instit...
View Trial →
NCT07073963
Recruiting

Virtual Patient Groups for Sarcoidosis Associated Fatigue

Enrollment
100 pts
Country
🇺🇸 United States
The Cleveland Clinic
View Trial →
NCT06085937 Phase 1
Recruiting

Feasibility and Safety of Ketamine for Suicidal Patients in the Emergency Department

Enrollment
50 pts
Country
🇺🇸 United States
Lindsay Maguire, MD
View Trial →
NCT04426461
Recruiting

Approach-Avoidance, Computational Framework for Predicting Behavioral Therapy Outcome (AAC-BeT)

Enrollment
220 pts
Country
🇺🇸 United States
Laureate Institute for Brain Resear...
View Trial →
NCT04713722
Recruiting

Early Life Stress and Depression: Molecular and Functional Imaging

Enrollment
160 pts
Country
🇺🇸 United States
Mclean Hospital
View Trial →
NCT05965245
Recruiting

Suubi-Mhealth: A Mobile Health Intervention to Address Depression Among Youth

Enrollment
278 pts
Country
🇺🇸 United States
Washington University School of Med...
View Trial →
NCT06500780
Recruiting

Equipping Patients Using Interventions for Pain and Depression

Enrollment
304 pts
Country
🇺🇸 United States
Indiana University
View Trial →
NCT06963463
Recruiting

Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

Enrollment
90 pts
Country
🇺🇸 United States
University of Pittsburgh
View Trial →
NCT05081596
Recruiting

A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD

Enrollment
100 pts
Country
🇺🇸 United States
Weill Medical College of Cornell Un...
View Trial →
NCT06576076
Recruiting

Cannabis, Linked Emotions, and Adolescent Risk Study

Enrollment
200 pts
Country
🇺🇸 United States
Massachusetts General Hospital
View Trial →
NCT05474846 Phase 2, Phase 3
Recruiting

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer

Enrollment
188 pts
Country
🇺🇸 United States
M.D. Anderson Cancer Center
View Trial →
NCT06839859 Phase 2
Recruiting

Family Acceptance Project Online (Pilot RCT)

Enrollment
180 pts
Country
🇺🇸 United States
University of Michigan
View Trial →
NCT06898788 EARLY_Phase 1
Recruiting

Probiotic Administration for Adolescent Depression

Enrollment
77 pts
Country
🇺🇸 United States
University of California, San Franc...
View Trial →

Frequently Asked Questions

How many depression clinical trials are active in United States?
There are currently 37 active clinical trials for depression with sites in United States, of which 37 are actively recruiting patients.
How can I join a depression clinical trial in United States?
To join a depression clinical trial in United States, select a recruiting trial below and check the eligibility criteria. Contact the trial's principal investigator or the listed site in United States directly. All trials listed here are sourced from ClinicalTrials.gov, the official U.S. registry of clinical studies.
What phases are depression trials in United States?
Active depression trials in United States span Phase 2, Phase 4, Phase 1, Phase 1, Phase 2, Phase 2, Phase 3, EARLY_Phase 1. Phase I trials test safety, Phase II test efficacy, and Phase III compare against standard treatments in larger patient populations.
Browse More
All United States Trials → Global depression Trials → All Countries → All Trials →