NCT05958667 Quitxt Mobile Text Messaging Cessation Research Study
| NCT ID | NCT05958667 |
| Status | Recruiting |
| Phase | — |
| Sponsor | The University of Texas Health Science Center at San Antonio |
| Condition | Smoking Cessation |
| Study Type | INTERVENTIONAL |
| Enrollment | 1,200 participants |
| Start Date | 2026-02-12 |
| Primary Completion | 2028-08 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 1,200 participants in total. It began in 2026-02-12 with a primary completion date of 2028-08.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The health benefits of smoking cessation by age 30 are much greater than cessation later in life, including gaining 10 years of life, compared with those who continue to smoke. The goal of the proposed study is to evaluate the effectiveness of the bilingual and culturally tailored Quitxt mobile cessation intervention. Quitxt provides interactive messages through texts or chat with visual and video content employing theory- and evidence-based techniques to prompt and sustain cessation. The study will recruit 1,200 Latino young adult smokers aged 18-29 who enroll and agree to make quit attempts, with half randomly assigned (like flipping a coin) to receive Quitxt and half to abbreviated text messages with smoking cessation-related content and referral to the Texas Department of State Health Services cessation program Yes Quit (which has diverse formats, but not explicitly tailored for young Latino adults in South Texas). Participants respond to baseline and follow-up assessments at one, three and six months after their enrollment, and those who report cessation will be asked to provide saliva samples to confirm they quit smoking. The sample size will be sufficient to detect expected higher cessation rates in those who are enrolled in Quitxt than those who are enrolled in Texas DSHS Yes Quit. The investigators will publish results in scientific journals, report them at scientific and community meetings, share them on social media, and publicize them widely. This study has the potential to advance public health by evaluating the effectiveness of a scalable, easily disseminated and adaptable intervention to help young adults, especially Latinos, quit smoking and reduce smoking-related cancer and chronic disease morbidity and mortality and their associated healthcare costs.
Eligibility Criteria
Inclusion Criteria: 1. Latinos 2. aged 18-29 years; 3. smoking at least one cigarette/day ≥3 days/week; 4. interested in quitting; 5. willing to provide follow-up data; 6. are not simultaneously participating in a cessation program; 7. own a cell phone or smartphone; 8. are able to send and receive text messages and access the Internet; 9. reside in the study area; and 10. able to provide informed consent to participate in the study. Exclusion Criteria: 1. are not interested in quitting; 2. are unable to provide consent due to a mental, emotional, or physical handicap that keep them from understanding the consent information; 3. do not own a cell phone with text and Internet capabilities; 4. are unable to respond to text messages and questions or unable to view the study mobile webpages/YouTube videos (i.e., if they are blind, deaf); or 5. are planning to move from the study area within the study time span.
Contact & Investigator
Patricia Chalela, DrPH
PRINCIPAL INVESTIGATOR
The University of Texas Health Science Center at San Antonio
Frequently Asked Questions
Who can join the NCT05958667 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 29 Years, studying Smoking Cessation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05958667 currently recruiting?
Yes, NCT05958667 is actively recruiting participants. Contact the research team at chalela@uthscsa.edu for enrollment information.
Where is the NCT05958667 trial being conducted?
This trial is being conducted at San Antonio, United States.
Who is sponsoring the NCT05958667 clinical trial?
NCT05958667 is sponsored by The University of Texas Health Science Center at San Antonio. The principal investigator is Patricia Chalela, DrPH at The University of Texas Health Science Center at San Antonio. The trial plans to enroll 1,200 participants.