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pain acute

Total Trials
5
Recruiting Now
5
Trial Phases
Phase 4

Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.

Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.

Frequently Asked Questions — pain acute Clinical Trials

How many clinical trials are currently recruiting for pain acute?
ClinicalMetric currently tracks 5 actively recruiting clinical trials for pain acute, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 5. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for pain acute?
pain acute research spans Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a pain acute clinical trial?
Eligibility criteria for pain acute trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 4
1
Top Sponsors
Ankara Etlik City Hospital 1 trial
Boston Children's Hospital 1 trial
Antonios Likourezos 1 trial
Özgül Aydemir 1 trial
Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal 1 trial

Recruiting Clinical Trials

NCT06534372
Recruiting
Affecting Factors for Chronic Pain After Sternotomy
Enrollment
500 pts
Location
Turkey (Türkiye)
Sponsor
Ankara Etlik City Hospital
View Trial →
NCT04439552
Recruiting
fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
Enrollment
60 pts
Location
United States
Sponsor
Boston Children's Hospital
View Trial →
NCT06364540 Phase 4
Recruiting
Nebulized Ketamine to Nebulized Fentanyl for Treating Acute Painful Conditions in the ED
Enrollment
150 pts
Location
United States
Sponsor
Antonios Likourezos
View Trial →
NCT07411417
Recruiting
Combined Acupressure Effects on Post-Thoracotomy Pain and Lung Volume
Enrollment
80 pts
Location
Turkey (Türkiye)
Sponsor
Özgül Aydemir
View Trial →
NCT06306183
Recruiting
Effect of Vitamin C on Pain Reduction After an Emergency Department Visit
Enrollment
204 pts
Location
Canada
Sponsor
Centre Integre Universitaire d...
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Related Conditions

pain chronic (2) cardiac surgery (1) sternotomy (1) pain postoperative (1) surgical injury (1) surgical wound (1) cornea injury (1) cornea (1) keratoconus (1) breathing mouth (1) relaxation diaphragm (1) cough (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: September 2026  ·  Data Methodology