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Medical Condition
pain acute
Total Trials
8
Recruiting Now
8
Trial Phases
Phase 2, Phase 4
Pain clinical trials span acute procedural pain, chronic musculoskeletal pain, neuropathic pain, and cancer-related pain β€” each requiring distinct trial designs and patient-reported outcome instruments. The regulatory demand for non-opioid alternatives has intensified the search for novel analgesic mechanisms, particularly ion channel targets and neurostimulation approaches.
Active trials evaluate Nav1.7/1.8 blockers, CGRP antagonists for new indications, spinal cord stimulation refinements, virtual reality-based pain management, and patient-specific ketamine infusion protocols. Pain trials increasingly use ecological momentary assessment (EMA) diary approaches over traditional recall-based pain rating scales.
Frequently Asked Questions — pain acute Clinical Trials
How many clinical trials are currently recruiting for pain acute?
ClinicalMetric currently tracks 8 actively recruiting clinical trials for pain acute, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 8. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for pain acute?
pain acute research spans Phase 2 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a pain acute clinical trial?
Eligibility criteria for pain acute trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2 1
Phase 4 1
Top Sponsors
1 trial
1 trial
1 trial
1 trial
1 trial
Recruiting Clinical Trials
NCT05263297
Recruiting
Enrollment
96 pts
Location
Turkey (Türkiye)
Sponsor
Karamanoğlu Mehmetbey Universi...
NCT05266040 Phase 2
Recruiting
Enrollment
60 pts
Location
United States
Sponsor
University of California, San ...
NCT06364540 Phase 4
Recruiting
Enrollment
150 pts
Location
United States
Sponsor
Antonios Likourezos
NCT06960317
Recruiting
Enrollment
204 pts
Location
United States
Sponsor
University of California, San ...
NCT05865327
Recruiting
Enrollment
24 pts
Location
Canada
Sponsor
Sunnybrook Health Sciences Cen...
NCT06539741
Recruiting
Enrollment
200 pts
Location
United States
Sponsor
University of Pennsylvania
NCT07144033
Recruiting
Enrollment
216 pts
Location
Hong Kong
Sponsor
Chinese University of Hong Kon...
NCT06306183
Recruiting
Enrollment
204 pts
Location
Canada
Sponsor
Centre Integre Universitaire d...
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: November 2026 · Data Methodology