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keratoconus

Total Trials
5
Recruiting Now
5
Trial Phases
Phase 2, Phase 2, Phase 3

ClinicalMetric tracks all active clinical trials for keratoconus sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — keratoconus Clinical Trials

How many clinical trials are currently recruiting for keratoconus?
ClinicalMetric currently tracks 5 actively recruiting clinical trials for keratoconus, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 5. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for keratoconus?
keratoconus research spans Phase 2 (2 trials), Phase 3 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a keratoconus clinical trial?
Eligibility criteria for keratoconus trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2
2
Phase 3
1
Top Sponsors
Cohen Laser and Vision Center 1 trial
Price Vision Group 1 trial
Oregon Health and Science University 1 trial
Instituto de Oftalmología Fundación Conde de Valenciana 1 trial
University Hospital, Montpellier 1 trial

Recruiting Clinical Trials

NCT05516004 Phase 2
Recruiting

Safety and Effectiveness of the PXL-Platinum 330 System for Cornea Crosslinking in Eyes With Cornea Thinning

Enrollment
300 pts
Location
United States
Sponsor
Cohen Laser and Vision Center
View Trial →
NCT03922542 Phase 2, Phase 3
Recruiting

Comparison of Standard vs. Accelerated Corneal Crosslinking

Enrollment
510 pts
Location
United States
Sponsor
Price Vision Group
View Trial →
NCT03504800
Recruiting

OCT in Diagnosis of Irregular Corneas

Enrollment
445 pts
Location
United States
Sponsor
Oregon Health and Science Univ...
View Trial →
NCT07372911
Recruiting

PRoTECT: Corneal Wavefront Guided PRK + Epi-off CXL vs. PTK+Epi-off CXL in Keratoconus

Enrollment
50 pts
Location
Mexico
Sponsor
Instituto de Oftalmología Fund...
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NCT05676580
Recruiting

Risk Factors and Progression of Keratoconus

Enrollment
200 pts
Location
France
Sponsor
University Hospital, Montpelli...
View Trial →
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology