← Browse by Condition
Medical Condition

keratoconus

Total Trials
7
Recruiting Now
7
Trial Phases
Phase 2

ClinicalMetric tracks all active clinical trials for keratoconus sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — keratoconus Clinical Trials

How many clinical trials are currently recruiting for keratoconus?
ClinicalMetric currently tracks 7 actively recruiting clinical trials for keratoconus, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 7. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for keratoconus?
keratoconus research spans Phase 2 (2 trials). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a keratoconus clinical trial?
Eligibility criteria for keratoconus trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 2
2
Top Sponsors
University of Aarhus 1 trial
Goodman Eye Center 1 trial
Oregon Health and Science University 1 trial
Oslo University Hospital 1 trial
Cohen Laser and Vision Center 1 trial

Recruiting Clinical Trials

NCT06921967
Recruiting
Effect of Corneal and Scleral RGP Lenses on Ocular Health and Visual Quality in Keratoconus
Enrollment
50 pts
Location
Denmark
Sponsor
University of Aarhus
View Trial →
NCT04094090 Phase 2
Recruiting
Safety and Effectiveness of the PXL-Platinum 330 System for Corneal Cross-Linking in Eyes With Corneal Ectasia
Enrollment
500 pts
Location
United States
Sponsor
Goodman Eye Center
View Trial →
NCT04570020
Recruiting
Scleral Lens Fitting Using Wide-Field OCT
Enrollment
258 pts
Location
United States
Sponsor
Oregon Health and Science Univ...
View Trial →
NCT06264024
Recruiting
Simultaneous pHototherapeutic Keratectomy and corneAl Collagen cRosslinking in Eyes With Keratoconus: a Randomized Trial (SHARK)
Enrollment
81 pts
Location
Norway
Sponsor
Oslo University Hospital
View Trial →
NCT05516004 Phase 2
Recruiting
Safety and Effectiveness of the PXL-Platinum 330 System for Cornea Crosslinking in Eyes With Cornea Thinning
Enrollment
300 pts
Location
United States
Sponsor
Cohen Laser and Vision Center
View Trial →
NCT06722937
Recruiting
The Collagen Factors of Rapid Progression of Keratoconus in Children.
Enrollment
160 pts
Location
China
Sponsor
Zhongshan Ophthalmic Center, S...
View Trial →
NCT04741230
Recruiting
Investigator Initiated, Prospective Study of Xenia Corneal Lenticule
Enrollment
15 pts
Location
United Kingdom
Sponsor
The Royal Wolverhampton Hospit...
View Trial →

Related Conditions

irregular astigmatism (1) pellucid marginal corneal degeneration (1) corneal ectasia (1) irregular contour of cornea (1) post laser retinal condition (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: November 2026  ·  Data Methodology