NCT07034599 Effects of Negative Pressure Ventilation Onto Hemodynamics and Right Ventricular Funktion in Patients After Implantation of a Left Ventricular Assist Device.
| NCT ID | NCT07034599 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Karlsburg Hospital |
| Condition | Critical Illness |
| Study Type | INTERVENTIONAL |
| Enrollment | 30 participants |
| Start Date | 2025-10-01 |
| Primary Completion | 2026-10-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 30 participants in total. It began in 2025-10-01 with a primary completion date of 2026-10-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
All patients undergoing an implantation of a durable left ventricular assist device and monitored by pulmonary artery catheter showing no adverse events after surgery are included in the study and ventilated for 15 minutes using extra thoracic negative pressure ventilation and usual intrathoracic positive pressure ventilation. Hemodynamics changes between both ventilation modes, especially focussing on right ventricular function and measured by a pulmonary artery catheter, are compared.
Eligibility Criteria
Inclusion Criteria: * All patients after implantation of a durable left ventricular assist device Exclusion Criteria: * Complication during surgery like bleeding, emergency, inability to fit the cuirass, unavailability of an investigator, unstable condition regarding circulation or ventilation
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07034599 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Critical Illness. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07034599 currently recruiting?
Yes, NCT07034599 is actively recruiting participants. Contact the research team at Heringlake@drguth.de for enrollment information.
Where is the NCT07034599 trial being conducted?
This trial is being conducted at Karlsburg, Germany.
Who is sponsoring the NCT07034599 clinical trial?
NCT07034599 is sponsored by Karlsburg Hospital. The trial plans to enroll 30 participants.