NCT07345169 IMMUNOREA - Immunological and Inflammatory Determinants Associated With the Prognosis of Intensive Care Patients
| NCT ID | NCT07345169 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Assistance Publique - Hôpitaux de Paris |
| Condition | Critical Illness |
| Study Type | OBSERVATIONAL |
| Enrollment | 540 participants |
| Start Date | 2026-01 |
| Primary Completion | 2031-02 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 540 participants in total. It began in 2026-01 with a primary completion date of 2031-02.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This is a prospective observational physiopathological study aimed at evaluating the immunological and inflammatory determinants associated with the prognosis of patients admitted to intensive care units (ICU). The study will establish multidimensional models predicting one-year survival and the occurrence of nosocomial infections. Patients admitted to ICU undergo routine biological sampling. In addition to these, minimal supplementary samples will be collected for immunological and inflammatory biomarker analysis at admission, day 1, day 4, day 8, ICU discharge or day 28, and at 12 months. Additional samples may be taken during clinically significant events (nosocomial infections, complications).
Eligibility Criteria
Inclusion Criteria: * Age ≥ 18 years * Admission to ICU within 24 hours Exclusion Criteria: * Moribund patient (ECOG=4) * Legal protection (guardianship/curatorship) * Uninsured patients * Pre-existing immunosuppression (active/recent cancer, hematologic disease, autoimmune disease, organ transplant, HIV) * Pregnant or breastfeeding women * Participation in another interventional trial * Patients under AME
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07345169 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Critical Illness. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07345169 currently recruiting?
Yes, NCT07345169 is actively recruiting participants. Contact the research team at charles.de-roquetaillade@aphp.fr for enrollment information.
Where is the NCT07345169 trial being conducted?
This trial is being conducted at Paris, France.
Who is sponsoring the NCT07345169 clinical trial?
NCT07345169 is sponsored by Assistance Publique - Hôpitaux de Paris. The trial plans to enroll 540 participants.