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Medical Condition

cocaine use disorder

Total Trials
5
Recruiting Now
5
Trial Phases
Phase 2, EARLY_Phase 1

ClinicalMetric tracks all active clinical trials for cocaine use disorder sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — cocaine use disorder Clinical Trials

How many clinical trials are currently recruiting for cocaine use disorder?
ClinicalMetric currently tracks 5 actively recruiting clinical trials for cocaine use disorder, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 5. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.
What trial phases are available for cocaine use disorder?
cocaine use disorder research spans Phase 1 (1 trial), Phase 2 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.
How do I find out if I qualify for a cocaine use disorder clinical trial?
Eligibility criteria for cocaine use disorder trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.
Trial Phases
Phase 1
1
Phase 2
1
Top Sponsors
The University of Texas Health Science Center, Houston 2 trials
Rajesh Narendran 1 trial
Icahn School of Medicine at Mount Sinai 1 trial
Wake Forest University Health Sciences 1 trial

Recruiting Clinical Trials

NCT07227948 Phase 2
Recruiting
Repurposing Semaglutide for the Treatment of Cocaine Use Disorder
Enrollment
75 pts
Location
United States
Sponsor
The University of Texas Health...
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NCT05011760 EARLY_Phase 1
Recruiting
[C-11]NPA PET-amphetamine in Cocaine Use Disorders
Enrollment
30 pts
Location
United States
Sponsor
Rajesh Narendran
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NCT05986578
Recruiting
Identifying Electrophysiological Targets for Transcranial Magnetic Stimulation in Cocaine Use Disorder
Enrollment
75 pts
Location
United States
Sponsor
The University of Texas Health...
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NCT07091877
Recruiting
Cocaine Cue-reactivity Incubation Study
Enrollment
252 pts
Location
United States
Sponsor
Icahn School of Medicine at Mo...
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NCT04927143
Recruiting
Encouraging Abstinence Behavior in a Drug Epidemic: Optimizing Dynamic Incentives
Enrollment
600 pts
Location
United States
Sponsor
Wake Forest University Health ...
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Related Conditions

opioid use disorder (1) opioid use (1) cocaine use (1) substance use (1) methamphetamine abuse (1) methamphetamine dependence (1)
ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology