NCT06641297 White Matter Plasticity in Schizophrenia
| NCT ID | NCT06641297 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Maryland, Baltimore |
| Condition | Schizophrenia Disorders |
| Study Type | INTERVENTIONAL |
| Enrollment | 36 participants |
| Start Date | 2025-01-02 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 36 participants in total. It began in 2025-01-02 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Schizophrenia spectrum disorders are associated with impairment in the microstructure of white matter, the key brain tissue responsible for fast communication between different brain regions necessary for any complex task. This white matter impairment is linked to problems with cognition in schizophrenia, especially slower processing speed. This project aims to study the potential for correcting white matter deficits in schizophrenia by examining mechanisms underlying white matter structure changes in response to training on playing a mock musical instrument.
Eligibility Criteria
Inclusion Criteria: * Diagnosis of schizophrenia, schizoaffective disorder, schizophreniform disorder, or psychosis NOS * age 15-45 * able to provide informed consent Exclusion Criteria: * contraindications to MRI (metal implants, claustrophobia) * medical condition that limits use of hands (ie, arthritis) * Active or recent (within 6 months) substance use disorder other than nicotine
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06641297 clinical trial?
This trial is open to participants of all sexes, aged 15 Years or older, up to 45 Years, studying Schizophrenia Disorders. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06641297 currently recruiting?
Yes, NCT06641297 is actively recruiting participants. Contact the research team at jchiappe@som.umaryland.edu for enrollment information.
Where is the NCT06641297 trial being conducted?
This trial is being conducted at Catonsville, United States, Catonsville, United States.
Who is sponsoring the NCT06641297 clinical trial?
NCT06641297 is sponsored by University of Maryland, Baltimore. The trial plans to enroll 36 participants.
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