NCT06322030 Weight Loss and ExeRcise for Post-stroke Veterans
| NCT ID | NCT06322030 |
| Status | Recruiting |
| Phase | — |
| Sponsor | VA Office of Research and Development |
| Condition | Stroke |
| Study Type | INTERVENTIONAL |
| Enrollment | 99 participants |
| Start Date | 2024-05-01 |
| Primary Completion | 2027-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 99 participants in total. It began in 2024-05-01 with a primary completion date of 2027-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Weight loss interventions for neurologically health individuals have established benefits for improving physical and psychosocial function. The investigators believe that Veterans who have had a stroke would realize similar benefits and that the effects would be enhanced with concurrent exercise training. The investigators will study the effects of a 15-week lifestyle management program to determine if it can effectively improve some of the physical and psychosocial problems common in Veterans who have had a stroke.
Eligibility Criteria
Inclusion Criteria: * A diagnosis of stroke at least 6 months prior * BMI \> 30 kg/m2 * Residual paresis in the lower extremity (Fugl-Meyer LE motor score \<34) * Ability to follow instructions, complete training and testing and to communicate exertion, pain and distress * Provision of informed consent * Individuals who meet inclusion criteria must complete an exercise tolerance test and be cleared for participation by the study cardiologist Exclusion Criteria: * Unable to ambulate at least 150 feet or experienced intermittent claudication while walking * Unstable cardiac arrhythmias, hypertrophic cardiomyopathy, severe aortic stenosis, angina or dyspnea at rest or during ADL's * Dementia * Life expectancy \<1 yr * History of DVT or pulmonary embolism within 6 months * Uncontrolled diabetes with recent weight loss, diabetic coma, or frequent insulin reactions * Severe hypertension with systolic \>200 mmHg and diastolic \>110 mmHg at rest * Current enrollment in a rehabilitation trial to enhance motor or psychosocial recovery
Contact & Investigator
Chris M Gregory, PhD
PRINCIPAL INVESTIGATOR
Ralph H. Johnson VA Medical Center, Charleston, SC
Frequently Asked Questions
Who can join the NCT06322030 clinical trial?
This trial is open to participants of all sexes, aged 40 Years or older, up to 80 Years, studying Stroke. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06322030 currently recruiting?
Yes, NCT06322030 is actively recruiting participants. Contact the research team at sarah.jackson@va.gov for enrollment information.
Where is the NCT06322030 trial being conducted?
This trial is being conducted at Charleston, United States.
Who is sponsoring the NCT06322030 clinical trial?
NCT06322030 is sponsored by VA Office of Research and Development. The principal investigator is Chris M Gregory, PhD at Ralph H. Johnson VA Medical Center, Charleston, SC. The trial plans to enroll 99 participants.
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