NCT07280481 Weekly Dynamics of Psychopathological and Symptom Networks During Mindfulness-Based Interventions for Emotional Distress
| NCT ID | NCT07280481 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Peking University |
| Condition | Depression, Anxiety |
| Study Type | INTERVENTIONAL |
| Enrollment | 500 participants |
| Start Date | 2025-11-16 |
| Primary Completion | 2026-04-28 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 500 participants in total. It began in 2025-11-16 with a primary completion date of 2026-04-28.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this clinical study is to learn how Mindfulness Intervention for Emotional Distress (MIED) helps people with emotional distress and how their symptoms and psychological patterns change over time. The main questions it aims to answer are: * How do the relationships between emotions, thoughts, and behaviors change week by week during mindfulness training? * Which psychological skills, such as distress tolerance or cognitive flexibility, improve first and lead to later emotional relief? Two groups will be compared - one that takes part in an online mindfulness intervention and one that waits to join - to see how the intervention changes emotional and psychological networks over time. Participants will: * Complete a 7-week online self-guided Mindfulness Intervention for Emotional Distress（iMIED） designed for people experiencing high emotional distress. * Fill out short weekly questionnaires about their emotions, thoughts, and behaviors before, during, and after the course (9 times in total). * Receive access to the mindfulness program after the study if they are in the wait-list group. This study includes about 500 adults aged 18 and older who feel anxious, depressed, or emotionally distressed but have no major psychiatric disorders. By tracking weekly changes, the research aims to identify how mindfulness intervention leads to emotional improvement and which skills play the most important roles in that process.
Eligibility Criteria
Inclusion Criteria: * experiencing emotional distress such as depression or anxiety (Kessler-10 score \> 21) Exclusion Criteria: * prior experience with mindfulness meditation * current self-harm or suicidal risk * bipolar disorder or schizophrenia * history of substance abuse * severe personal trauma history
Contact & Investigator
Xinghua Liu
PRINCIPAL INVESTIGATOR
School of Psychological and Cognitive Sciences, Peking University
Frequently Asked Questions
Who can join the NCT07280481 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Depression, Anxiety. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07280481 currently recruiting?
Yes, NCT07280481 is actively recruiting participants. Contact the research team at 514100919@qq.com for enrollment information.
Where is the NCT07280481 trial being conducted?
This trial is being conducted at Beijing, China.
Who is sponsoring the NCT07280481 clinical trial?
NCT07280481 is sponsored by Peking University. The principal investigator is Xinghua Liu at School of Psychological and Cognitive Sciences, Peking University. The trial plans to enroll 500 participants.
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