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Recruiting Phase 2 NCT06858189

NCT06858189 Promoting Active Therapy: Path to Wellness

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Clinical Trial Summary
NCT ID NCT06858189
Status Recruiting
Phase Phase 2
Sponsor Kansas State University
Condition Depression, Anxiety
Study Type INTERVENTIONAL
Enrollment 60 participants
Start Date 2025-02-28
Primary Completion 2026-05-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 65 Years
Study Type INTERVENTIONAL
Interventions
Walk-and-talk therapy

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.

This trial targets 60 participants in total. It began in 2025-02-28 with a primary completion date of 2026-05-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This project will examine changes in depression and anxiety following a 10-week intervention promoting nature-based physical activity in mental health settings. We will recruit ten licensed therapists whose caseload includes adults with depression and anxiety. Following a training by our team, each participating therapist will recruit six clients, who will be randomly assigned to the intervention or control condition. Clients in the intervention condition will engage in walk-and-talk therapy outdoors during weekly sessions and discuss strategies for being active outdoors on their own. We will assess changes in depression, anxiety, and nature-based physical activity in both groups.

Eligibility Criteria

Inclusion Criteria: * Current client of a participating therapist who has completed study training * Diagnosed depressive or anxiety disorder * Able to safely engage in moderate physical activity * Willing to complete all study requirements Exclusion Criteria: * Planning to discontinue therapy in less than 6 months * Active suicidal ideation * Does not pass exercise risk screener

Contact & Investigator

Central Contact

Emily L Mailey, PhD

✉ emailey@ksu.edu

📞 847-224-1199

Frequently Asked Questions

Who can join the NCT06858189 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 65 Years, studying Depression, Anxiety. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT06858189 trial and what does that mean for participants?

Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.

Is NCT06858189 currently recruiting?

Yes, NCT06858189 is actively recruiting participants. Contact the research team at emailey@ksu.edu for enrollment information.

Where is the NCT06858189 trial being conducted?

This trial is being conducted at Manhattan, United States.

Who is sponsoring the NCT06858189 clinical trial?

NCT06858189 is sponsored by Kansas State University. The trial plans to enroll 60 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology