NCT05625425 Wayfinding Intervention and Long-Term Memory
| NCT ID | NCT05625425 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of California, San Francisco |
| Condition | Long-Term Memory Decline |
| Study Type | INTERVENTIONAL |
| Enrollment | 200 participants |
| Start Date | 2024-01-01 |
| Primary Completion | 2026-12-31 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 200 participants in total. It began in 2024-01-01 with a primary completion date of 2026-12-31.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Therapeutic treatment is yet available for declining memory, which is an impairment affecting the quality of life for many older adults and patients with cognitive impairment. Cognitive training with an immersive video game promises to drive hippocampal-cortical plasticity and associated gains that can restore memory capability or provide therapeutic treatment for memory deficits.
Eligibility Criteria
Inclusion Criteria: * fluent speakers of English * completed 12 or more years of education * normal or corrected-to-normal vision * dexterity to comfortably operate the scanner-compatible response box * freedom from physical and neurological conditions contra-indicated for fMRI * must confirm physical stamina and comfort for semi-weekly brisk 30-minute walks on level ground Exclusion Criteria: * use of psychotropic medications * history of concussions or dizziness, vestibular or balance problems * significant discomfort with virtual reality experiences
Contact & Investigator
Peter E Wais, PhD
PRINCIPAL INVESTIGATOR
Neuroscape, Department of Neurology
Frequently Asked Questions
Who can join the NCT05625425 clinical trial?
This trial is open to participants of all sexes, aged 60 Years or older, up to 85 Years, studying Long-Term Memory Decline. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05625425 currently recruiting?
Yes, NCT05625425 is actively recruiting participants. Contact the research team at twist.study@ucsf.edu for enrollment information.
Where is the NCT05625425 trial being conducted?
This trial is being conducted at San Francisco, United States.
Who is sponsoring the NCT05625425 clinical trial?
NCT05625425 is sponsored by University of California, San Francisco. The principal investigator is Peter E Wais, PhD at Neuroscape, Department of Neurology. The trial plans to enroll 200 participants.