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Recruiting NCT06934876

Waveform Capnography Compared to Colorimetric Carbon Dioxide Detection During Tracheal Intubation of Critically Ill Adults

◆ AI Clinical Summary

This study compares two methods of checking whether a breathing tube has been placed correctly in the windpipe during emergency intubation: waveform capnography (a machine that measures carbon dioxide) and colorimetric detection (a color-changing indicator). The research will determine which method is better at confirming the tube is in the right position.

Key Objective: This trial tests whether one method for confirming correct breathing tube placement is more reliable than the other, potentially improving safety during emergency intubation in critically ill patients.

Who to Consider: Critically ill adults requiring emergency intubation and mechanical ventilation in an intensive care setting should consider enrolling.

Trial Parameters

Condition Acute Respiratory Failure
Sponsor Brian Driver
Study Type OBSERVATIONAL
Phase N/A
Enrollment 1,332
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2025-04-21
Completion 2026-12-01
Interventions
Colorimetric carbon dioxide (CO2) detectionWaveform capnography

Brief Summary

This study will compare the sensitivity and specificity of waveform capnography versus colorimetric carbon dioxide detection to identify tracheal placement of the endotracheal tube during intubation of critically ill adults.

Eligibility Criteria

Inclusion Criteria: 1. Patient is located in a participating unit (ED or ICU) 2. Patient is undergoing tracheal intubation. 3. The clinician intends to use an exhaled CO2 detection device to confirm tracheal placement of the tube. Exclusion Criteria: 1. Patient is known to be a prisoner 2. Patient is known to be \< 18 years old 3. A responsible clinician has determined that sole use of either waveform capnography or colorimetric testing is required for optimal care of the patient.

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