Medical Condition

acute respiratory failure

Total Trials

10

Recruiting Now

10

Trial Phases

Phase 2, Phase 4

ClinicalMetric tracks all active clinical trials for acute respiratory failure sourced from ClinicalTrials.gov. Research in this area spans early-phase safety investigations through large Phase 3 confirmatory trials, conducted by NIH-funded academic centers, independent investigators, and pharmaceutical sponsors worldwide. Each listing is updated daily as new studies open enrollment and existing ones reach capacity or complete follow-up.

Trial listings include the NCT identifier, current recruitment status, phase classification, primary and secondary endpoints, estimated enrollment size, participating countries, and direct links to the full protocol on ClinicalTrials.gov. Eligibility criteria — including age range, disease stage, and prior treatment requirements — are documented for every study to help patients and clinicians assess suitability before contacting a trial site.

Frequently Asked Questions — acute respiratory failure Clinical Trials

How many clinical trials are currently recruiting for acute respiratory failure?

ClinicalMetric currently tracks 10 actively recruiting clinical trials for acute respiratory failure, sourced in real time from ClinicalTrials.gov. The total number of registered studies—including those not yet enrolling or in active follow-up—is 10. Trial availability changes daily as new studies open enrollment and existing ones reach capacity.

What trial phases are available for acute respiratory failure?

acute respiratory failure research spans Phase 2 (1 trial), Phase 4 (1 trial). Phase 1 studies evaluate safety and dosing in small groups, Phase 2 studies assess preliminary efficacy in 100–300 participants, and Phase 3 trials compare the new treatment against the standard of care in 300–3,000+ patients. Phase 4 post-approval studies monitor long-term outcomes in real-world populations.

How do I find out if I qualify for a acute respiratory failure clinical trial?

Eligibility criteria for acute respiratory failure trials vary by study and typically specify age range, disease stage or severity, prior treatment history, and specific diagnostic or laboratory parameters. Each listing on ClinicalMetric links to the full protocol on ClinicalTrials.gov, where inclusion and exclusion criteria are documented. Contact the sponsoring site's research coordinator directly to confirm your eligibility—your treating physician or specialist can also help identify the most appropriate trial based on your medical history and current treatment status.

Trial Phases

Phase 2

Phase 4

Top Sponsors

University of Modena and Reggio Emilia 2 trials

Pär Johansson 1 trial

Università degli Studi del Piemonte Orientale Amedeo Avogadro 1 trial

Hospices Civils de Lyon 1 trial

The Institute of Molecular and Translational Medicine, Czech Republic 1 trial

Recruiting Clinical Trials

NCT06989385

Recruiting

CORALINE - Correlation Between Physiological and Clinical Variables and Failure of Non-Invasive Respiratory Support in Patients With Acute Respiratory Failure

University of Modena and Reggi...

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NCT06319274 Phase 2

Recruiting

Infusion of Prostacyclin vs Placebo for 72-hours in Mechanically Ventilated Patients With Acute Respiratory Failure

Acute DYSPnea in the Emergency Department: Diagnostic Value of Point-of-care UltraSound

Università degli Studi del Pie...

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NCT04666246

Recruiting

Inspiratory Effort in COVID-19

University of Modena and Reggi...

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NCT07532811

Recruiting

Evaluation of Perfusion and Ventilation Distribution in Children: a Pilot Study.

Hospices Civils de Lyon

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NCT06189924

Recruiting

Exhaled Breath Condensate Analysis in Mechanically Ventilated Patients

The Institute of Molecular and...

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NCT05670093

Recruiting

Neural Pressure Support, Synchrony and Respiratory Muscle Unloading

Karolinska Institutet

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NCT06750536

Recruiting

Evaluating the Safety and Performance of the MiniLung Petite Kit in Neonatal and Pediatric Patients With Acute Respiratory and Cardiac Failure

External Validation of the BREF Models

Istituto Clinico Humanitas

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NCT06881927 Phase 4

Recruiting

Eduction in ImmunoSuppressive Regimen Among Kidney Transplant Recipients Patients Admitted to the Intensive Care Unit for Septic Shock and/or Acute Respiratory Failure

University Hospital, Strasbour...

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Related Conditions

endothelial dysfunction (1) pulmonary infection (1) hydrostatic pulmonary edema (1) dyspnea (1) covid19 (1) critical illness (1) extracorporeal membrane oxygenation complication (1) neonatal aspiration pneumonia (1) acute lung injury (1) oxygen inhalation therapy (1) respiratory distress (1) sepsis and septic shock (1)

ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer · Last Reviewed: September 2026 · Data Methodology