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Recruiting NCT06340646

Washington University Participant Engagement and Cancer Genomic Sequencing Center (WU-PE-CGS)

Trial Parameters

Condition Cholangiocarcinoma
Sponsor Washington University School of Medicine
Study Type INTERVENTIONAL
Phase N/A
Enrollment 990
Sex ALL
Min Age 18 Years
Max Age N/A
Start Date 2022-10-18
Completion 2027-01-31
Interventions
Return of Genetic Results: Biomarker information from cancer cellsReturn of Genetic Results: Inherited mutations related to cancerReturn of Genetic Results: Inherited mutations related to other medical issues

Brief Summary

The overall goal of the WU-PE-CGS is to build a rigorous, scientific evidence base for approaches that direct engagement of cancer patients and post-treatment cancer survivors as participants in cancer research, and to investigate the impact of directly engaging participants in decisions regarding returning of genomic results on participants' health and satisfaction. Participants in this study will be presented with the choice of types of genomic results to receive, and the Engagement Optimization Unit (EOU) will investigate the impact of this intervention on participant knowledge, expectations of benefit, personal utility, and decisional conflict.

Eligibility Criteria

Eligibility Criteria: * Patients with cholangiocarcinoma, multiple myeloma, or early onset colon or rectal cancer. * If diagnosed with multiple myeloma, must be African-American. * If diagnosed with colon or rectal cancer, must be African-American AND must be no older than 65 years old at the time of diagnosis. * At least 18 years old * Able to understand and willing to sign an IRB-approved written informed consent document

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