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Recruiting Phase 2 NCT05423158

NCT05423158 Virtual Care Strategies to Improve Participation in Cardiac Rehabilitation Among Veterans

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Clinical Trial Summary
NCT ID NCT05423158
Status Recruiting
Phase Phase 2
Sponsor VA Office of Research and Development
Condition Cardiovascular Diseases
Study Type INTERVENTIONAL
Enrollment 150 participants
Start Date 2023-03-15
Primary Completion 2026-06-30

Eligibility & Interventions

Sex All sexes
Min Age 21 Years
Max Age N/A
Study Type INTERVENTIONAL
Interventions
d-Coaching

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

In Phase 2, researchers evaluate early signs of effectiveness. You may be randomized to receive the active treatment or a comparator. Monitoring continues closely.

This trial targets 150 participants in total. It began in 2023-03-15 with a primary completion date of 2026-06-30.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Home-based CR (HBCR) is an alternative to traditional CR programs that has comparable efficacy in improving morbidity/mortality and increases access to critical services. There is major potential to improve Veteran engagement in CR by combining digital coaching (d-Coaching) with existing VA-supported technologies. The investigator's theory-based intervention targets a critical component of successful CR engagement that is not available through traditional programs: virtual social support through a social network. In addition, the investigators propose to improve self-efficacy and self-regulation through interactive digital multi-media education, personalized feedback, and motivation so that Veterans can complete the prescribed HBCR program and maintain physical activity long-term. This RCT will evaluate the effects of HBCR alone (usual care) versus HBCR + d-Coaching, including a private group with direct messaging on the Connecteam mobile application and bimonthly engagement sessions via VA Video Connect. The investigators will randomly assign 150 Veterans from 2 HBCR programs to a 3-month intervention. The addition of d- Coaching to existing digital technologies will be operationalized by using a private social media group to provide social support, education, personalized feedback, and motivation. The investigators aim to determine the effect of the d-Coaching intervention on: a) the number of completed HBCR sessions over 3 months, b) functional capacity, c) physical activity, c) psychosocial outcomes, d) clinical outcomes, and e) social cognitive factors of self-efficacy, self-regulation, and perceived social support over 6 months. The investigators will also evaluate the extent to which self-efficacy, self-regulation, and perceived social support mediate the effect of the intervention on function and physical activity.

Eligibility Criteria

Inclusion Criteria: 1. 21 years of age 2. History of cardiovascular disease that qualified participant for CR (MI, percutaneous coronary intervention, coronary artery bypass grafting, heart failure, valve surgery) 3. Referral to participate in home-based Phase II CR. Exclusion Criteria: 1. Participation in center-based Phase II CR. 2. Cognitive impairment (per Mini-Cog) 3. Lack of English proficiency/literacy (Digital coaching will be conducted in English. Participants will need to speak/read English to receive intervention.) 4. Unstable clinical conditions (e.g., unstable arrhythmias or heart block, active infection, uncontrolled hypertension, decompensated heart failure, unstable angina, etc.)

Contact & Investigator

Central Contact

Linda G Park, PhD MS NP

✉ Linda.Park@va.gov

📞 (925) 348-2174

Principal Investigator

Linda Grace Park, PhD MS NP

PRINCIPAL INVESTIGATOR

San Francisco VA Medical Center, San Francisco, CA

Frequently Asked Questions

Who can join the NCT05423158 clinical trial?

This trial is open to participants of all sexes, aged 21 Years or older, studying Cardiovascular Diseases. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

What phase is the NCT05423158 trial and what does that mean for participants?

Phase 2 trials evaluate whether the treatment shows signs of effectiveness while continuing to monitor safety. More participants are enrolled than in Phase 1 to help refine the treatment protocol.

Is NCT05423158 currently recruiting?

Yes, NCT05423158 is actively recruiting participants. Contact the research team at Linda.Park@va.gov for enrollment information.

Where is the NCT05423158 trial being conducted?

This trial is being conducted at San Francisco, United States, Decatur, United States.

Who is sponsoring the NCT05423158 clinical trial?

NCT05423158 is sponsored by VA Office of Research and Development. The principal investigator is Linda Grace Park, PhD MS NP at San Francisco VA Medical Center, San Francisco, CA. The trial plans to enroll 150 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology