NCT07646249 VENtilation Modalities During Transport of PostoperatIve CRITically Ill Patients to the ICU
| NCT ID | NCT07646249 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva |
| Condition | Respiration, Artificial |
| Study Type | OBSERVATIONAL |
| Enrollment | 800 participants |
| Start Date | 2026-09-07 |
| Primary Completion | 2027-10-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 800 participants in total. It began in 2026-09-07 with a primary completion date of 2027-10-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Patients undergoing major non-cardiac surgery may require postoperative mechanical ventilation and transfer from the operating room to the intensive care unit (ICU). This intra-hospital transport phase is critical, as patients may experience changes in respiratory and hemodynamic status, including alterations in oxygenation, ventilation, blood pressure, and heart rate. During transport, ventilatory support may be provided using different strategies, including manual ventilation with a bag-valve device or mechanical ventilation with a portable ventilator. Although both approaches are commonly used in clinical practice, there is limited evidence comparing their effects on respiratory function, gas exchange, and overall physiological stability during and after transport. This multicenter, prospective observational study aims to describe current clinical practices in ventilatory support during intra-hospital transport in adult patients undergoing non-cardiac surgery who require ICU admission. The study will also evaluate changes in vital signs, arterial blood gas parameters, and respiratory mechanics, as well as the occurrence of adverse events during transport and postoperative pulmonary complications within the first five days after surgery. No additional interventions or procedures beyond standard clinical care will be performed. All data will be collected as part of routine clinical practice. The results of this study are expected to improve the understanding of ventilation management during transport and to identify safer and more effective strategies for critically ill postoperative patients.
Eligibility Criteria
Inclusion criteria * Intubated patients undergoing general anesthesia for non-cardiac surgery * Requirement for postoperative IMV * Age ≥18 years * Obtained informed consent Exclusion criteria * Patients undergoing cardiac surgery * Patients receiving preoperative mechanical ventilation prior to surgery.
Contact & Investigator
RICERCA SIAARTI Ufficio Ricerca Clinica, Clinical Trial Office
✉ ricerca@siaarti.it📞 0039 06 4452816
Frequently Asked Questions
Who can join the NCT07646249 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Respiration, Artificial. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07646249 currently recruiting?
Yes, NCT07646249 is actively recruiting participants. Contact the research team at ricerca@siaarti.it for enrollment information.
Where is the NCT07646249 trial being conducted?
This trial is being conducted at Alessandria, Italy.
Who is sponsoring the NCT07646249 clinical trial?
NCT07646249 is sponsored by Societa Italiana Anestesia Analgesia Rianimazione e Terapia Intensiva. The trial plans to enroll 800 participants.