NCT05541887 Use Muscadine Wine Nutraceuticals to Improve Brain Health, Cognition, and Mental Health
| NCT ID | NCT05541887 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Florida |
| Condition | Cognitive Performance |
| Study Type | INTERVENTIONAL |
| Enrollment | 25 participants |
| Start Date | 2023-08-30 |
| Primary Completion | 2026-12 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 25 participants in total. It began in 2023-08-30 with a primary completion date of 2026-12.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Previous studies have shown that polyphenol-rich foods can positively affect cognitive functions, memory, and mood in humans. We hypothesize that both acute and chronic intake of muscadine wine polyphenols will improve cognitive performance and mood through regulating the HPA axis, alleviating inflammation and oxidative stress, and/or inhibiting monoamine oxidase activities
Eligibility Criteria
Inclusion Criteria: * Healthy * BMI (18.5-29.9) * Body weight ≥110 pounds Exclusion Criteria: * Pregnancy * Breast-feeding * Smokers * Diabetic * Heavy drinkers * Subjective but not clinically diagnosed cognitive impairment (Montreal cognitive assessment score \<26), * Inability to understand the cognitive function tasks * Intake of medication that might influence the outcome of the study (e.g. psychostimulant) * cannabis product user * Clinically diagnosed mental illnesses * Cardiovascular and neurological disorders * Uncontrolled hypertension
Contact & Investigator
Liwei Gu, PhD
PRINCIPAL INVESTIGATOR
University of Florida
Frequently Asked Questions
Who can join the NCT05541887 clinical trial?
This trial is open to participants of all sexes, aged 50 Years or older, up to 65 Years, studying Cognitive Performance. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05541887 currently recruiting?
Yes, NCT05541887 is actively recruiting participants. Contact the research team at cmai1@ufl.edu for enrollment information.
Where is the NCT05541887 trial being conducted?
This trial is being conducted at Gainesville, United States.
Who is sponsoring the NCT05541887 clinical trial?
NCT05541887 is sponsored by University of Florida. The principal investigator is Liwei Gu, PhD at University of Florida. The trial plans to enroll 25 participants.