Trial Parameters
Brief Summary
In a transvaginal tru-cut biopsy, guided by ultrasound, a needle is inserted through the vaginal wall into a pelvic lesion and a few pieces of tissue are obtained for examination. This clinical trial is organized to evaluate the safety and efficacy of transvaginal tru-cut biopsy in a large group of patients with tumors in the small pelvis.
Eligibility Criteria
Inclusion Criteria: * 1\. Following lesion criteria applicable for biopsy: 1. Lesion safely accessible (no visceral or vessel interposition; in the case of a transvaginal approach no vaginal stenosis (severe atrophy - virgo - vaginismus); within reach of biopsy needle) 2. Solid component present (purely cystic lesions excluded) 2\. Biopsy for research purposes, the following is applicable: Patients with a gynecological tumor eligible for participation in academic or commercial clinical trials requesting a biopsy for translational research. For the current study, which is observational, we do not intend to take additional biopsies outside routine clinical practice, but only biopsies requested for participation in other (interventional) studies on systemic treatment in gynecologic oncology. 3\. In case of a diagnostic biopsy, one of the following inclusion criteria should be applicable: <!-- --> 1. Suspicious primary disseminated gynecologic tumor (tumor itself or metastasis) Patients wi