NCT06567535 Treatment of Mandibular Bone Cyst by Navigation and Endoscopy
| NCT ID | NCT06567535 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
| Condition | Jaw Cysts |
| Study Type | INTERVENTIONAL |
| Enrollment | 122 participants |
| Start Date | 2024-08-20 |
| Primary Completion | 2026-11-10 |
Eligibility & Interventions
Eligibility Fast-Check
Enter your details for a quick preliminary check. This does not replace medical advice.
What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 122 participants in total. It began in 2024-08-20 with a primary completion date of 2026-11-10.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
In this study, with the assistance of endoscopic technology and intraoperative navigation technology, the removal and curettage of large odontogenic jaw cyst occurred in the mandible were performed to reduce the rate of postoperative nerve injury. In this study, the investigators compared the efficacy of traditional extraction and curettage with endoscopic navigation assistance in the treatment of giant mandibular bone cysts. In this study, the rate of inferior alveolar nerve injury 1 month after surgery was taken as the main outcome index, and the recurrence rate 1 year after surgery was taken as the secondary outcome index, to explore whether endoscopic combined with intraoperative navigation-assisted treatment of giant mandibular bone cyst could achieve lower postoperative nerve injury rate and postoperative recurrence rate.
Eligibility Criteria
Inclusion Criteria: 1. They are between 18 and 75 years old 2. Imaging and puncture pathology showed odontogenic cystic lesion of the mandible 3. Cystic lesions greater than or equal to 2cm in diameter and spread to the inferior alveolar nerve 4. New or recurrent cyst lesions, or odontogenic cystic lesions that are still greater than or equal to 2cm after other treatment such as fenestration and affecting the lower alveolar nerve 5. No serious systemic disease, tolerant of general anesthesia 6. Patients undergoing surgical treatment for mandibular bone cysts under general anesthesia 7. There was no inferior alveolar nerve injury before operation 8. Have not participated in other clinical trials within 30 days 9. Patients who volunteer to participate in the program and sign informed consent Exclusion Criteria: 1. The patient has severe systemic disease or pregnancy, and is judged to be unable to tolerate the course of this clinical study and cannot tolerate general anesthesia after evaluation by the research team and multidisciplinary consultation 2. Inability to complete the entire clinical research process due to personal, social, and economic reasons 3. Patients with psychiatric disorders or inability to perceive and communicate normally, such as schizophrenia, claustrophobia, etc., are unable to complete the examination and cooperate in the entire clinical research process
Contact & Investigator
Yan Wang
PRINCIPAL INVESTIGATOR
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Frequently Asked Questions
Who can join the NCT06567535 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 75 Years, studying Jaw Cysts. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06567535 currently recruiting?
Yes, NCT06567535 is actively recruiting participants. Contact the research team at wangy573@mail.sysu.edu.cn for enrollment information.
Where is the NCT06567535 trial being conducted?
This trial is being conducted at Guangzhou, China.
Who is sponsoring the NCT06567535 clinical trial?
NCT06567535 is sponsored by Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University. The principal investigator is Yan Wang at Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University. The trial plans to enroll 122 participants.