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Recruiting NCT07424716

NCT07424716 Bone Regeneration Using PRF After Cyst Enucleation

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Clinical Trial Summary
NCT ID NCT07424716
Status Recruiting
Phase
Sponsor Sana'a University
Condition Odontogenic Cyst
Study Type INTERVENTIONAL
Enrollment 20 participants
Start Date 2025-05-19
Primary Completion 2026-04-19

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 80 Years
Study Type INTERVENTIONAL
Interventions
Autologous Platelet-Rich Fibrin (PRF)Conventional Surgical Management

Eligibility Fast-Check

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What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 20 participants in total. It began in 2025-05-19 with a primary completion date of 2026-04-19.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

This randomized controlled clinical trial aims to evaluate the clinical efficacy of autologous platelet-rich fibrin (PRF) in promoting osseous regeneration following cystic enucleation in the jaws. The study will assess bone healing outcomes and compare PRF application with conventional management methods.

Eligibility Criteria

Inclusion Criteria: * Patients diagnosed with odontogenic cysts requiring surgical enucleation. * Presence of a postoperative osseous defect in the jaws after cyst enucleation. * Age ≥ 18 years. * Systemically healthy patients (ASA I or II). * Patients willing to participate and sign informed consent. Exclusion Criteria: * Patients with systemic diseases affecting bone healing (e.g., uncontrolled diabetes, osteoporosis). * Patients receiving bisphosphonates or long-term corticosteroid therapy. * Smokers (\>10 cigarettes/day). * Pregnant or lactating women. * Patients with acute infection at the surgical site. * Patients unwilling to participate or unable to attend follow-up visits.

Frequently Asked Questions

Who can join the NCT07424716 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Odontogenic Cyst. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07424716 currently recruiting?

Yes, NCT07424716 is actively recruiting participants. Visit ClinicalTrials.gov or contact Sana'a University to inquire about joining.

Where is the NCT07424716 trial being conducted?

This trial is being conducted at Sanaa, Yemen.

Who is sponsoring the NCT07424716 clinical trial?

NCT07424716 is sponsored by Sana'a University. The trial plans to enroll 20 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: July 2026  ·  Data Methodology