NCT07453186 Transabdominal and Laparoscopic Ultrasound in a Bariatric Setting
| NCT ID | NCT07453186 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Esbjerg Hospital - University Hospital of Southern Denmark |
| Condition | Gallstone Disease |
| Study Type | INTERVENTIONAL |
| Enrollment | 130 participants |
| Start Date | 2026-04-01 |
| Primary Completion | 2028-06-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 130 participants in total. It began in 2026-04-01 with a primary completion date of 2028-06-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Every year, many patients undergo weight-loss (bariatric) surgery. While this surgery leads to significant and intended weight loss, it also increases the risk of developing gallstones or other gallbladder problems. Approximately one in five patients later requires a second operation to remove the gallbladder. This type of surgery carries a higher risk of complications and reoperations compared with gallbladder surgery performed in the general population. Preventive treatment may help reduce this risk. One option is medical treatment with Ursochol, which has been shown to lower the risk of developing gallstones after bariatric surgery. However, this treatment is only effective in patients who have not already developed gallstones before surgery. This means patients need a reliable preoperative ultrasound examination of the gallbladder. Unfortunately, performing ultrasound can be technically challenging in patients with obesity, making it harder to detect small stones or other abnormalities. The goal is therefore to improve the examination of the gallbladder in patients undergoing bariatric surgery in order to better identify who may benefit from preventive treatment. The study The investigators are comparing two types of ultrasound examination of the gallbladder: * Standard ultrasound performed on the outside of the abdomen using a handheld probe. * Laparoscopic ultrasound performed during bariatric surgery using a small ultrasound probe placed inside the abdomen, typically placed on the liver near the gallbladder. It is of interest to find out whether the ultrasound performed during surgery finds more: * Gallstones * Sludge * Small stones (microlithiasis) * Thickening of the gallbladder wall By improving detection, the investigators aim to better guide preventive treatment and reduce the need for future gallbladder surgery.
Eligibility Criteria
Inclusion Criteria: * Age ≥18 years * Scheduled for bariatric surgery * Able to provide informed consent Exclusion Criteria: * Previous cholecystectomy * Previous biliary surgery * Previous liver surgery * Inability to provide informed consent
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07453186 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Gallstone Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07453186 currently recruiting?
Yes, NCT07453186 is actively recruiting participants. Contact the research team at benjamin.drejer.petersen@rsyd.dk for enrollment information.
Where is the NCT07453186 trial being conducted?
This trial is being conducted at Esbjerg, Denmark.
Who is sponsoring the NCT07453186 clinical trial?
NCT07453186 is sponsored by Esbjerg Hospital - University Hospital of Southern Denmark. The trial plans to enroll 130 participants.