NCT05556902 Therapeutic Mechanisms of Epidural Spinal Cord Stimulation
| NCT ID | NCT05556902 |
| Status | Recruiting |
| Phase | — |
| Sponsor | University of Alabama at Birmingham |
| Condition | Blood Pressure |
| Study Type | INTERVENTIONAL |
| Enrollment | 80 participants |
| Start Date | 2022-08-02 |
| Primary Completion | 2029-05-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 80 participants in total. It began in 2022-08-02 with a primary completion date of 2029-05-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The purpose of this study in patients undergoing routine care epidural spinal cord stimulation (SCS) is to determine 1) whether SCS reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension, 2) whether higher baseline BP (i.e., hypertension) predicts reductions in pain following SCS, and finally 3) whether different SCS waveforms elicits stimulus-evoked compound action potentials (ECAPs) in spinal cord and at the cortex (electroencephalography, and magnetoenchphalography).
Eligibility Criteria
Inclusion Criteria: 1. Male or Female, age 18-89 2. Chronic pain for more than 3 months 3. Willing to visit a research lab 4. Willing to undergo a blood draw 5. Able to provide written informed consent Exclusion Criteria 1. History of neurological disease (e.g., dementias, Parkinson's) 2. History of stroke 3. Current diagnosis of cancer 4. Subject is unwilling or unable to comply with the protocol
Contact & Investigator
Marshall Holland, MD
PRINCIPAL INVESTIGATOR
The University of Alabama at Birmingham
Frequently Asked Questions
Who can join the NCT05556902 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 89 Years, studying Blood Pressure. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05556902 currently recruiting?
Yes, NCT05556902 is actively recruiting participants. Contact the research team at clgonzalez@uabmc.edu for enrollment information.
Where is the NCT05556902 trial being conducted?
This trial is being conducted at Birmingham, United States.
Who is sponsoring the NCT05556902 clinical trial?
NCT05556902 is sponsored by University of Alabama at Birmingham. The principal investigator is Marshall Holland, MD at The University of Alabama at Birmingham. The trial plans to enroll 80 participants.