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Recruiting NCT04173416

NCT04173416 The Youth Opioid Recovery Support (YORS) Intervention

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Clinical Trial Summary
NCT ID NCT04173416
Status Recruiting
Phase
Sponsor Potomac Health Foundations
Condition Opioid-use Disorder
Study Type INTERVENTIONAL
Enrollment 150 participants
Start Date 2020-02-17
Primary Completion 2026-08-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 28 Years
Study Type INTERVENTIONAL
Interventions
Youth Opioid Recovery Support (YORS)

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 150 participants in total. It began in 2020-02-17 with a primary completion date of 2026-08-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Youth are disproportionately affected by the current opioid crisis with catastrophic consequences, and young adults with opioid use disorder (OUD) often struggle with adherence to relapse prevention medications. The Youth Opioid Recovery Support (YORS) model is a promising, innovative, wrap-around approach that addresses barriers to medication adherence and treatment engagement in an effort to improve public health outcomes in this vulnerable young adult population. This study seeks to refine the YORS intervention through stakeholder input and pilot iterative testing followed by an efficacy randomized controlled trial. This project will significantly contribute to our knowledge base of practical strategies to address the opioid crisis.

Eligibility Criteria

Inclusion Criteria: * Age 18-28 * OUD diagnosis * Willing (intending) to receive treatment with XR-NTX or XR-BUP under the care of a MTC physician/nurse practitioner * Willingness to designate family member (or other suitable treatment significant other) for treatment involvement (i.e., a treatment significant other; TSO) Exclusion Criteria: * Psychiatric or medical instability (e.g., suicidality, psychosis, Sickle Cell disease with frequent crises) that would preclude participation in the trial * Living situation (location greater than 75 miles from the center, homelessness) that would preclude participation in the trial

Contact & Investigator

Central Contact

Marc Fishman, MD

✉ mjfishman@comcast.net

📞 410-233-1400

Principal Investigator

Marc Fishman, MD

PRINCIPAL INVESTIGATOR

Maryland Treatment Centers

Frequently Asked Questions

Who can join the NCT04173416 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 28 Years, studying Opioid-use Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT04173416 currently recruiting?

Yes, NCT04173416 is actively recruiting participants. Contact the research team at mjfishman@comcast.net for enrollment information.

Where is the NCT04173416 trial being conducted?

This trial is being conducted at Baltimore, United States.

Who is sponsoring the NCT04173416 clinical trial?

NCT04173416 is sponsored by Potomac Health Foundations. The principal investigator is Marc Fishman, MD at Maryland Treatment Centers. The trial plans to enroll 150 participants.

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ClinicalMetric — Independent clinical trial intelligence platform. Not affiliated with NIH, ClinicalTrials.gov, the U.S. FDA, or any pharmaceutical company, hospital, or clinical research organization. Trial data is sourced from ClinicalTrials.gov for informational purposes only and does not constitute medical advice. Do not make any treatment, enrollment, or health decisions based solely on information found here — always consult a qualified healthcare professional. Full Disclaimer  ·  Last Reviewed: April 2026  ·  Data Methodology