NCT06758817 The Triad of Nutrition, Intestinal Microbiota and Rheumatoid Arthritis (TASTY)
| NCT ID | NCT06758817 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa |
| Condition | Diet Interventions |
| Study Type | INTERVENTIONAL |
| Enrollment | 100 participants |
| Start Date | 2023-01-02 |
| Primary Completion | 2025-09-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 100 participants in total. It began in 2023-01-02 with a primary completion date of 2025-09-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The main goal of this trial is to investigate whether a dietary intervention based on a typical Mediterranean Diet enriched with fermented foods (MedDiet+) can impact gut microbiota and RA-related outcomes.
Eligibility Criteria
Inclusion Criteria: * RA patients (ACR/EULAR2010 criteria) * Age \>18-years * Disease duration \>1-year * Active disease (DAS28 \> 2.6units) * On stable medication for 12 weeks * Low/medium MedDiet adherence (PREDIMED\<10) * Willing to comply with study protocol Exclusion Criteria: * Prednisolone dose ≥ 7.5 mg/day * Antibiotic therapy 4-weeks prior to baseline * Persistent use of NSAID's * Inflammatory or irritable bowel disease * Celiac disease * Chronic diarrhea * Diabetes * Other immune-mediated inflammatory diseases besides RA * Major organ dysfunction * Cancer diagnosed in the last five years * Health conditions which may difficult participation (cognitive impairment/psychiatric disease) * Pregnant or lactating individuals
Contact & Investigator
Catarina Sousa Guerreiro, RD PhD
PRINCIPAL INVESTIGATOR
Nutrition Lab, Faculty of Medicine, University of Lisbon
Frequently Asked Questions
Who can join the NCT06758817 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Diet Interventions. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06758817 currently recruiting?
Yes, NCT06758817 is actively recruiting participants. Contact the research team at cfguerreiro@medicina.ulisboa.pt for enrollment information.
Where is the NCT06758817 trial being conducted?
This trial is being conducted at Lisbon, Portugal, Lisbon, Portugal.
Who is sponsoring the NCT06758817 clinical trial?
NCT06758817 is sponsored by Lisbon Academic Medical Center - Centro Académico de Medicina de Lisboa. The principal investigator is Catarina Sousa Guerreiro, RD PhD at Nutrition Lab, Faculty of Medicine, University of Lisbon. The trial plans to enroll 100 participants.