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Recruiting NCT07138313

NCT07138313 Dietary Impact on Sleep, Rhythms and Related Physiology

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Clinical Trial Summary
NCT ID NCT07138313
Status Recruiting
Phase
Sponsor Uppsala University
Condition Sleep
Study Type INTERVENTIONAL
Enrollment 24 participants
Start Date 2025-09-22
Primary Completion 2027-07-31

Eligibility & Interventions

Sex All sexes
Min Age 18 Years
Max Age 32 Years
Study Type INTERVENTIONAL
Interventions
Low-fat dietary interventionHigh-fat dietary intervention

Eligibility Fast-Check

Enter your details for a quick preliminary check. This does not replace medical advice.

What to Expect as a Participant

You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.

This trial targets 24 participants in total. It began in 2025-09-22 with a primary completion date of 2027-07-31.

⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.

Brief Summary

Sleep and metabolism are closely interconnected, and emerging evidence suggests that dietary composition may influence both sleep quality and key physiological functions such as glucose regulation, cardiovascular activity, and hormonal signaling. This study aims to investigate how a Western-style unhealthy diet versus a healthier, fiber-rich diet affects objective and subjective sleep measures, 24-hour physiological parameters, and a range of biomarkers related to cardiometabolic, neurodegenerative, and gut microbial function.

Eligibility Criteria

Inclusion Criteria: * Age 18-32 yr * Healthy (self-reported) and not on chronic medication * BMI 18-27 kg/m2 (and waist circumference \<102 cm), and weight stable (less than 5% body weight change in the past 6 months) * Non-smoker and non-nicotine user * Regular sleep-wake pattern, with sleep duration of 7-9.25 hrs per night * Regular exercise habits the last 2 months * Regular daily meal pattern with 3 main meals Exclusion Criteria: * Major or chronic illness, e.g. diabetes, renal disease or inflammatory bowel disease * Current or history of endocrine or metabolic disorders * Psychiatric or neurological disorders (e.g. bipolar disorder, epilepsy) * Frequent gastrointestinal symptoms * Chronic medication * Any sleep disorder (including recent or chronic symptoms of insomnia) * Shift work in the preceding three months or for a long duration * Extreme chronotype or physical activity patterns * Time travel over two time zones in the preceding month * Too much weight gain or weight loss in the preceding 6 months (±5% body weight in past 6 months) * Any issues with or allergies against the provided food items * Recent major dietary changes or adoption of specific dietary regimens * Women who are pregnant, breastfeeding, or planning to become pregnant during the study period. * Use of illicit drugs or substances of abuse

Contact & Investigator

Central Contact

Jonathan Cedernaes, MD, PhD

✉ jonathan.cedernaes@medsci.uu.se

📞 0184710000

Principal Investigator

Jonathan Cedernaes, MD, PhD

PRINCIPAL INVESTIGATOR

Uppsala University, Sweden

Frequently Asked Questions

Who can join the NCT07138313 clinical trial?

This trial is open to participants of all sexes, aged 18 Years or older, up to 32 Years, studying Sleep. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.

Is NCT07138313 currently recruiting?

Yes, NCT07138313 is actively recruiting participants. Contact the research team at jonathan.cedernaes@medsci.uu.se for enrollment information.

Where is the NCT07138313 trial being conducted?

This trial is being conducted at Uppsala, Sweden.

Who is sponsoring the NCT07138313 clinical trial?

NCT07138313 is sponsored by Uppsala University. The principal investigator is Jonathan Cedernaes, MD, PhD at Uppsala University, Sweden. The trial plans to enroll 24 participants.

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