Trial Parameters
Condition Essential Tremor
Sponsor Karolinska Institutet
Study Type INTERVENTIONAL
Phase N/A
Enrollment 100
Sex ALL
Min Age 18 Years
Max Age 75 Years
Start Date 2018-06-30
Completion 2026-01-30
Interventions
Deep Brain StimulationBest Medical Treatment
Brief Summary
To evaluate the effect of deep brain stimulation (DBS) vs best medical treatment in essential tremor (ET) in a randomized, single-blinded controlled trial.
Eligibility Criteria
Inclusion Criteria: * Diagnosis of ET, as decided by the movement disorder specialist; Substantial incapacity; Duration of symptoms \> 5 years; Age 18 - 75; unsatisfying effect from β-blockers, or be unable to tolerate the medical therapy. Exclusion Criteria: * Cognitive impairment; Co-morbidity or non-compliance likely to jeopardize the result or to confuse the evaluation; Normal surgical exclusion criteria.