NCT04828798 Directional Versus Nondirectional DBS for ET
| NCT ID | NCT04828798 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Oregon Health and Science University |
| Condition | Essential Tremor |
| Study Type | INTERVENTIONAL |
| Enrollment | 24 participants |
| Start Date | 2021-04-01 |
| Primary Completion | 2027-10-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 24 participants in total. It began in 2021-04-01 with a primary completion date of 2027-10-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This will be a single center (OHSU) proof of concept trial to demonstrate that directional deep brain stimulation (DBS) creates a larger therapeutic window for the treatment of essential tremor (ET), effectively treats ET, and minimizes effects on speech, gait and balance compared to nondirectional DBS.
Eligibility Criteria
Inclusion Criteria: * A tremor syndrome of bilateral upper limb action tremor with at least 3 years' duration Exclusion Criteria: * Patients who have decided not to receive DBS for control of their medication-refractory essential tremor. * Patients with secondary tremor (ie not Essential Tremor), such as side effects from medications, secondary to another identified neurologic disease (eg multiple sclerosis, -----Parkinson's disease, dystonia). * Prior history of deep brain stimulation. * Prior history of thalamotomy. * A history or signs of dystonia, ataxia or parkinsonism. * Task specific tremor. * Orthostatic tremor. * Patients with cardiac pacemakers, defibrillators, or neurostimulators. * Patients who require MRI, ECT, rTMS, or diathermy. * Subjects with other type of neurological disease or injury.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT04828798 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, up to 80 Years, studying Essential Tremor. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT04828798 currently recruiting?
Yes, NCT04828798 is actively recruiting participants. Contact the research team at fanningz@ohsu.edu for enrollment information.
Where is the NCT04828798 trial being conducted?
This trial is being conducted at Portland, United States.
Who is sponsoring the NCT04828798 clinical trial?
NCT04828798 is sponsored by Oregon Health and Science University. The trial plans to enroll 24 participants.