NCT05317390 Clinical Validation of DystoniaNet Deep Learning Platform for Diagnosis of Isolated Dystonia
| NCT ID | NCT05317390 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Massachusetts Eye and Ear Infirmary |
| Condition | Dystonia |
| Study Type | INTERVENTIONAL |
| Enrollment | 1,000 participants |
| Start Date | 2022-06-01 |
| Primary Completion | 2028-04-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
You will actively receive the study intervention — which may be a drug, biologic, device, or procedure.
This trial targets 1,000 participants in total. It began in 2022-06-01 with a primary completion date of 2028-04-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This research involves retrospective and prospective studies for clinical validation of a DystoniaNet deep learning platform for the diagnosis of isolated dystonia.
Eligibility Criteria
Inclusion criteria: 1. Males and females of diverse racial and ethnic backgrounds, with age across the lifespan; 2. Patients will have at least one of the forms of dystonia, including focal dystonia (e.g., laryngeal, cervical, oromandibular, blepharospasm, focal hand, musicians), segmental dystonia, or generalized dystonia; 3. Patients will have other movement disorders (Parkinson's disease, essential tremor, dyskinesia, myoclonus) and other non-neurological conditions (tic disorders, torticollis, ulnar nerve entrapments, temporomandibular disorders, dysphonia) that mimic dystonic symptoms. Exclusion criteria: 1. Patients who are incapable of giving informed consent; 2. Patients who are unable to undergo brain MRI due to the presence of certain tattoos and ferromagnetic objects in their bodies (e.g., implanted stimulators, surgical clips, prosthesis, artificial heart valve) that cannot be removed or due to pregnancy or breastfeeding at the time of the study.
Contact & Investigator
Kristina Simonyan, MD, PhD
PRINCIPAL INVESTIGATOR
Massachusetts Eye and Ear
Frequently Asked Questions
Who can join the NCT05317390 clinical trial?
This trial is open to participants of all sexes, studying Dystonia. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT05317390 currently recruiting?
Yes, NCT05317390 is actively recruiting participants. Contact the research team at simonyan_lab@meei.harvard.edu for enrollment information.
Where is the NCT05317390 trial being conducted?
This trial is being conducted at Boston, United States.
Who is sponsoring the NCT05317390 clinical trial?
NCT05317390 is sponsored by Massachusetts Eye and Ear Infirmary. The principal investigator is Kristina Simonyan, MD, PhD at Massachusetts Eye and Ear. The trial plans to enroll 1,000 participants.