NCT07085247 The Role of Cutibacterium Acnes in the Development of Degenerative Lumbar Intervertebral Disc Disease
| NCT ID | NCT07085247 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Masaryk University |
| Condition | Lumbar Disc Herniation |
| Study Type | OBSERVATIONAL |
| Enrollment | 400 participants |
| Start Date | 2025-06-01 |
| Primary Completion | 2028-06-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 400 participants in total. It began in 2025-06-01 with a primary completion date of 2028-06-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this study is to clarify the role of the bacterium Cutibacterium acnes in the development of degenerative disc disease in patients with lumbar disc herniation who underwent microdiscectomy as part of their regular medical care.
Eligibility Criteria
Inclusion Criteria: * minimum age of 18 years * MRI of the lumbosacral spine performed one month ± 2weeks before surgery showing a disc protrusion, herniation, or free nucleus pulposus sequestration * matching physical examination findings including positive straight leg raise test, dermatomal sensory deficits, myotome motor deficits, and diminished deep tendon reflexes. Exclusion Criteria: * antibiotics or corticosteroid use the month before surgery * ongoing bacterial or viral infection * immunocompromised patient * trauma * undefined radiological mass * inflammatory arthritis * other rheumatologic diseases.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07085247 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Lumbar Disc Herniation. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07085247 currently recruiting?
Yes, NCT07085247 is actively recruiting participants. Contact the research team at peter.solar@fnusa.cz for enrollment information.
Where is the NCT07085247 trial being conducted?
This trial is being conducted at Brno, Czechia.
Who is sponsoring the NCT07085247 clinical trial?
NCT07085247 is sponsored by Masaryk University. The trial plans to enroll 400 participants.