NCT07543588 The Physiotherapy Assessment of Breathing Pattern Disorder
| NCT ID | NCT07543588 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Royal Brompton & Harefield NHS Foundation Trust |
| Condition | Breathing Pattern Disorder |
| Study Type | OBSERVATIONAL |
| Enrollment | 150 participants |
| Start Date | 2024-12-10 |
| Primary Completion | 2026-05-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 150 participants in total. It began in 2024-12-10 with a primary completion date of 2026-05-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to evaluate a clinical tool called the Breathing Pattern Assessment Tool (BPAT), which is used by physiotherapists to assess breathing pattern disorder (BPD). BPD is a condition where breathing is inefficient or out of sync with the body's needs, leading to symptoms such as breathlessness. The study will investigate whether the BPAT is a reliable and accurate way to identify and assess BPD, and whether it can be used to monitor changes over time, particularly following physiotherapy treatment. It will also compare BPAT scores with other commonly used questionnaires that measure breathlessness and breathing symptoms. Participants will include patients with BPD, patients with asthma, and healthy individuals. Patients with BPD will attend physiotherapy sessions as part of their usual care, during which their breathing will be assessed using the BPAT at different time points, including before and after treatment. Healthy participants will attend a single assessment visit, and asthma participants' data will be collected from routine clinical care. The study will also explore whether BPAT scores change following treatment and whether these changes reflect improvements reported by patients and clinicians. In addition, a small number of patients and physiotherapists will be invited to take part in interviews to share their experiences of the assessment process and treatment. This will help understand whether the BPAT is acceptable and useful in clinical practice. Overall, this study aims to improve how breathing pattern disorder is assessed and monitored, which may help guide better treatment for patients in the future.
Eligibility Criteria
Inclusion Criteria (Breathing Pattern Disorder group) * Adults aged above 18 years * Outpatient referrals for 'unexplained breathlessness' or possible breathing pattern disorder * Primary BPD (no other significant respiratory or cardiology diagnosis) * Secondary BPD (patients with a diagnosis of asthma) * Able to complete up to four sessions of outpatient physiotherapy intervention Exclusion Criteria * Patients with a respiratory diagnosis including COPD, ILD, Bronchiectasis and Cystic Fibrosis or structural heart disease * Pregnancy * Unable to give informed consent * Anyone currently participating in pulmonary/cardiac rehabilitation * Anyone receiving specialist ENT speech and language therapy for Upper airway symptoms
Contact & Investigator
Lizzie Grillo JF Clinical Specialist Physiotherapist, BSc MSc
✉ lizzie.grillo1@nhs.net📞 07843203979
Lizzie JF Grillo, BSc MSc
PRINCIPAL INVESTIGATOR
Royal Brompton and Harefield Hospital
Frequently Asked Questions
Who can join the NCT07543588 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Breathing Pattern Disorder. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07543588 currently recruiting?
Yes, NCT07543588 is actively recruiting participants. Contact the research team at lizzie.grillo1@nhs.net for enrollment information.
Where is the NCT07543588 trial being conducted?
This trial is being conducted at London, United Kingdom.
Who is sponsoring the NCT07543588 clinical trial?
NCT07543588 is sponsored by Royal Brompton & Harefield NHS Foundation Trust. The principal investigator is Lizzie JF Grillo, BSc MSc at Royal Brompton and Harefield Hospital. The trial plans to enroll 150 participants.