NCT07025070 The Link Between Physical Activity and Brain Health in Healthy Adults
| NCT ID | NCT07025070 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Technical University of Madrid |
| Condition | Alzheimer Disease |
| Study Type | OBSERVATIONAL |
| Enrollment | 60 participants |
| Start Date | 2024-11-25 |
| Primary Completion | 2026-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 60 participants in total. It began in 2024-11-25 with a primary completion date of 2026-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
The goal of this observational study is to investigate the cross-sectional relationship between physical activity and brain health from a multiscale approach (neuropsychology, neuroimaging, peripheral biomarkers and genetics) in former athletes and sedentary individuals. The main question it aims to answer is: Do former athletes have better brain structure than sedentary people? Evaluating the differences in neurodegenerative processes between competitive training and sedentary and inactivity.
Eligibility Criteria
Inclusion Criteria: * Group A: ex-athletes and continue to perform regular physical exercise (minimum 3 days/week of moderate-vigorous intensity). * Group B: sedentary individuals, (i.e., perform \<150 min of moderate intensity exercise per week or IPAQ score\<600 MET min/week). * In both groups (A and B) the conditions of physical exercise or sedentary lifestyle must have been maintained for at least 6 months prior to the evaluations. * Not having a history of neurological or psychiatric disorder or suffering from a serious medical condition Exclusion Criteria: * Medical conditions that have a high risk of associated cognitive symptoms. * Severe head injury with loss of consciousness within the previous 5 years. * Alcoholism (\>3 alcoholic drinks per day). * Chronic use of anxiolytics, neuroleptics, narcotics, anticonvulsants, or sedative hypnotics. * Hearing or visual impairment that would preclude testing * History of neurological disease with clinically relevant impact on cognition (e.g. cerebrovascular disease). * Incidental structural brain findings with impact on cognitive impairment or survival (e.g., malignant brain tumor). * Presence of severe systemic disease (e.g., cancer under treatment). * Consumption of anabolic substances. * Problems understanding spoken or written Spanish. * Those with pacemakers or metallic implants that may interfere with the MRI.
Contact & Investigator
Frequently Asked Questions
Who can join the NCT07025070 clinical trial?
This trial is open to participants of all sexes, aged 40 Years or older, up to 75 Years, studying Alzheimer Disease. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07025070 currently recruiting?
Yes, NCT07025070 is actively recruiting participants. Contact the research team at songxin.tang@alumnos.upm.es for enrollment information.
Where is the NCT07025070 trial being conducted?
This trial is being conducted at Madrid, Spain.
Who is sponsoring the NCT07025070 clinical trial?
NCT07025070 is sponsored by Technical University of Madrid. The trial plans to enroll 60 participants.
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