NCT07541222 The Impact of Multiple Antihypertensive Therapy on Post-Induction Hypotension Burden in Cardiac Surgery Patients
| NCT ID | NCT07541222 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Konya City Hospital |
| Condition | Hypotension on Induction |
| Study Type | OBSERVATIONAL |
| Enrollment | 160 participants |
| Start Date | 2026-05-01 |
| Primary Completion | 2026-11-01 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 160 participants in total. It began in 2026-05-01 with a primary completion date of 2026-11-01.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
This study aims to investigate the impact of multiple preoperative antihyperstensive drug use on the burden of post-induction hypotension (PIH) in patients undergoing elective cardiac surgery. The researchers will observe whether the combination of different antihypertensive classes (such as ACE inhibitors, ARBs, beta-blockers, and calcium channel blockers) leads to a higher incidence and severity of blood pressure drops and increased need for vasoactive support during the period between anesthesia induction and surgical incision.
Eligibility Criteria
Inclusion Criteria: * Adult patients aged 40 years and older * Undergoing elective cardiac surgery (e.g., isolated CABG, isolated valve surgery, or combined CABG+valve surgery via sternotomy) * Regular use of at least one antihypertensive medication for at least 4 weeks prior to the operation date * Voluntary participation and signed informed consent Exclusion Criteria: * Emergency surgery * Preoperative shock or requirement for high-dose inotropic/vasopressor therapy * End-stage liver or kidney failure * Uncontrolled hypertension * Difficult intubation or prolonged induction process * Ejection fraction less than 35%
Contact & Investigator
Mustafa Aydemir, MD
PRINCIPAL INVESTIGATOR
Konya City Hospital
Frequently Asked Questions
Who can join the NCT07541222 clinical trial?
This trial is open to participants of all sexes, aged 40 Years or older, studying Hypotension on Induction. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT07541222 currently recruiting?
Yes, NCT07541222 is actively recruiting participants. Contact the research team at drmustafaaydemir02@gmail.com for enrollment information.
Where is the NCT07541222 trial being conducted?
This trial is being conducted at Konya, Turkey (Türkiye).
Who is sponsoring the NCT07541222 clinical trial?
NCT07541222 is sponsored by Konya City Hospital. The principal investigator is Mustafa Aydemir, MD at Konya City Hospital. The trial plans to enroll 160 participants.