NCT06138340 The Effects of Anesthetics on Brain Network Connectivity in Patients With Supratentorial Glioma
| NCT ID | NCT06138340 |
| Status | Recruiting |
| Phase | — |
| Sponsor | Beijing Tiantan Hospital |
| Condition | Brain Network Connectivity |
| Study Type | OBSERVATIONAL |
| Enrollment | 120 participants |
| Start Date | 2023-08-31 |
| Primary Completion | 2025-11-30 |
Eligibility & Interventions
Eligibility Fast-Check
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What to Expect as a Participant
This is an observational study. You will not receive an experimental treatment; researchers will collect data based on your existing condition or standard treatment.
This trial targets 120 participants in total. It began in 2023-08-31 with a primary completion date of 2025-11-30.
⚠ This information is for research awareness only. Always consult your physician before joining any clinical trial. Participation is voluntary and you may withdraw at any time.
Brief Summary
Perioperative anesthesia can affect postoperative cognitive function. In our previous study, intraoperative dexmedetomidine (Dex) infusion reduced the incidence of delirium within the first 5 days after brain tumor. However, the mechanism is still unclear. With the development of neuroimaging, multimodal neuroimaging technology provide a new method to explore the underlying mechanism. Therefore, the purpose of this study is to analyze the alterations of brain network under sedation and anesthesia by different anesthetics in patients with supratentorial glioma and their association with cognition.
Eligibility Criteria
Inclusion Criteria: * Diagnosed as unilateral supratentorial glioma by MRI * Selective operation * Age over 18 years old * ASA I-II * Right handedness Exclusion Criteria: * History of cerebrovascular disease, brain trauma, chemotherapy and radiotherapy, or psychotropic drugs * History of intracranial surgery * Drug and/or alcohol abuse * History of dementia or mental illness * Pregnant or lactating women * Contraindications for MRI * Severe bradycardia (heart rate less than 40 beats per minute), sick sinus syndrome or second-to-third degree atrioventricular block * Severe hepatic or renal dysfunction
Contact & Investigator
Frequently Asked Questions
Who can join the NCT06138340 clinical trial?
This trial is open to participants of all sexes, aged 18 Years or older, studying Brain Network Connectivity. Full inclusion and exclusion criteria are listed in the Eligibility Criteria section. Always confirm your eligibility with the research team before applying.
Is NCT06138340 currently recruiting?
Yes, NCT06138340 is actively recruiting participants. Contact the research team at florapym766@163.com for enrollment information.
Where is the NCT06138340 trial being conducted?
This trial is being conducted at Beijing, China.
Who is sponsoring the NCT06138340 clinical trial?
NCT06138340 is sponsored by Beijing Tiantan Hospital. The trial plans to enroll 120 participants.